No-touch recipient hepatectomy in liver transplantation for liver malignancies: A state-of-the-art review.

Hepatobiliary Pancreat Dis Int

NHC Key Laboratory of Combined Multi-Organ Transplantation, Institute of Organ Transplantation, Zhejiang University, Hangzhou 310003, China; School of Clinical Medicine, Hangzhou Medical College, Hangzhou 310059, China; Institute of Translational Medicine, Zhejiang University, Hangzhou 310000, China. Electronic address:

Published: October 2024

Tumor recurrence, the Gordian knot of liver transplantation for malignancies, may be attributed to many parameters. The technique of the "classical" recipient hepatectomy is believed to be one of the potential reasons to cause tumor evasion because of the possible increase of circulating tumor cells, thus leading to an increased recurrent rate. On this background, the no-touch oncological recipient hepatectomy technique has been developed. A comprehensive review of the development and the key surgical steps of the no-touch recipient hepatectomy is presented. This technique might improve clinical outcomes, especially for those recipients who are at a high risk for tumor recurrence. Multicenter prospective studies should be set up to further validate the prognostic role of this technique in patients with liver cancer treated with liver transplantation.

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Source
http://dx.doi.org/10.1016/j.hbpd.2024.10.004DOI Listing

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