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Carcinoid heart findings in vasoactive intestinal peptide-secreting tumour. | LitMetric

Carcinoid heart findings in vasoactive intestinal peptide-secreting tumour.

BMJ Case Rep

Division of Cardiology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.

Published: November 2024

AI Article Synopsis

  • - Diagnosis of tricuspid valve disease in patients with carcinoid heart syndrome is often done with echocardiography, especially in those already diagnosed with carcinoid syndrome.
  • - VIPoma is a rare type of tumor occurring in 0.05%-2% of cases, causing symptoms like flushing, diarrhea, and electrolyte issues without typically affecting heart valves.
  • - In a notable case, detection of tricuspid regurgitation and stenosis during echocardiography led to a quicker investigation for cancer, ultimately revealing the presence of VIPoma.

Article Abstract

Tricuspid valve disease in carcinoid heart syndrome is usually diagnosed via screening echocardiography in patients with known carcinoid syndrome. Vasoactive intestinal peptide tumour (VIPoma) is a rare tumour with an incidence of 0.05%-2% that typically presents with symptoms related to the release of vasoactive intestinal peptide: flushing, diarrhoea and electrolyte abnormalities like hypokalaemia and hypochlorhydria. Historically, the cardiac valves are unaffected. We present a case where a finding of tricuspid regurgitation and stenosis on echocardiography prompted an expedited workup for malignancy ultimately leading to a diagnosis of VIPoma.

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Source
http://dx.doi.org/10.1136/bcr-2024-262229DOI Listing

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