LX9211, a rising star for relieving of diabetic peripheral neuropathic pain.

J Diabetes Investig

Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Published: November 2024

AI Article Synopsis

  • - LX9211 showed significant pain reduction in diabetic peripheral neuropathy (DPN) patients during a multicenter trial, with noticeable relief reported by the first week at a 10 mg dose.
  • - Higher doses of LX9211 were less effective, but side effects like dizziness and nausea were mostly mild.
  • - The results underscore the need to investigate both drug-based and natural treatment options, like flavonoids, for managing DPN.

Article Abstract

In a multicenter trial, LX9211 significantly reduced pain in diabetic peripheral neuropathy (DPN) patients, with the 10 mg dose showing notable relief by the first week. Although the higher dose was less effective, side effects like dizziness and nausea were generally mild. These findings highlight the importance of exploring both pharmaceutical and natural treatments, such as flavonoids, for managing DPN.

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Source
http://dx.doi.org/10.1111/jdi.14342DOI Listing

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