Lichen sclerosus (LS) is a chronic inflammatory disorder that predominantly affects the genital region of postmenopausal women, often resulting in significant morbidity due to pruritus and pain. Extragenital manifestations are rare and can present a diagnostic challenge. We report a case of a 65-year-old female presenting with white papules and plaques, some with a cribriform appearance, in an acral distribution. We detail the dermoscopic findings observed and provide a review of the relevant published literature on this topic.
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| http://dx.doi.org/10.7759/cureus.70995 | DOI Listing |
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2024 British Association for Sexual Health and HIV (BASHH) UK national guideline on the management of vulval conditions.
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Genitourinary and HIV Medicine and BASHH Clinical Effectiveness Group, Central North West London NHS Foundation Trust, London, UK.
Background: The management of vulval disorders in Genitourinary Medicine (GUM) clinics requires targeted approaches due to the wide range of conditions affecting the vulva. Vulval diseases encompass various aetiologies, including dermatoses, pain syndromes, and pre-malignant conditions, necessitating specialized care often involving multidisciplinary collaboration.
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Division of Urology, Department of Surgery, University of Alberta, Edmonton, Alberta.
Introduction: Ideal treatment of lichen sclerosus (LS) induced penile urethral strictures (PUS) remains elusive. The objective of this study is to compare multi-institutional outcomes of single-stage urethroplasty (SSU) with oral mucosal graft (OMG), staged urethroplasty and perineal urethrostomy (PU) for treatment of LS induced PUS.
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View Article and Find Full Text PDFImmune Dysregulation and Cellular Composition in Lichen Sclerosus Revealed by Integrative Epigenetic Analysis with Cell Type Deconvolution.
J Inflamm Res
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Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education; Key Laboratory of Innovation and Transformation of Advanced Medical Devices, Ministry of Industry and Information Technology; National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering); School of Engineering Medicine, Beihang University, Beijing, 100191, People's Republic of China.
Background: Lichen sclerosus (LS) is a chronic inflammatory disease affecting skin and mucosal tissues, particularly external genitalia, with a risk of cancer. Its etiology is unknown, possibly involving immune dysregulation and inflammation.
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