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Enhancing home-based physical activity for neurodivergent children: adapting the program with AI and universal design.
Front Physiol
January 2025
School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Purpose: While it is common practice for schools across the United States to include neurodivergent children in physical education classes, many programs outside of school-such as those at home or in the community-are not effectively tailored to meet their support needs. This gap contributes to lower levels of physical activity among neurodivergent children. Our objective was to address this issue by systematically adapting the program to enable neurodivergent children to safely engage in physical activity at home.
View Article and Find Full Text PDFBonding performance of universal adhesive systems with dual-polymerising resin cements to various dental substrates: in vitro study.
BMC Oral Health
January 2025
Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8549, Japan.
Background: Resin cements often require substrate-specific pretreatment. Recently, universal adhesive systems have been introduced, simplifying procedures by eliminating the need for multiple adhesives and offering options that do not require light curing. This study investigated the bonding performance of universal adhesive systems combined with dual-polymerising resin cements on enamel, dentin, zirconia, lithium disilicate ceramics (LDS), and resin blocks.
View Article and Find Full Text PDFThe international symposium ASOBIOTICS 2024 brought together scientists across disciplines to discuss the challenges of advancing antibacterial antisense oligomers (ASOs) from basic research to clinical application. Hosted by the Helmholtz Institute for RNA-based Infection Research (HIRI) in Wurzburg, Germany, on September 12-13th, 2024, the event featured presentations covering major milestones and current challenges of this antimicrobial technology and its applications against pathogens, commensals, and bacterial viruses. General design principles and modification of ASOs based on peptide nucleic acid (PNA) or phosphorodiamidate-morpholino-oligomer (PMO) chemistry, promising cellular RNA targets, new delivery technologies, as well as putative resistance mechanisms were discussed.
View Article and Find Full Text PDFThe multi-scale complexity of human genetic variation beyond continental groups.
bioRxiv
December 2024
Centro de Ciencias Genómicas, UNAM, Cuernavaca, México.
Traditional clustering and visualization approaches in human genetics often operate under frameworks that assume inherent, discrete groupings. These methods can inadvertently simplify multifaceted relationships, functioning to entrench the idea of typological groups. We introduce a network-based pipeline and visualization tool grounded in relational thinking, which constructs networks from a variety of genetic similarity metrics.
View Article and Find Full Text PDFPacing system analyzers to guide conduction system pacing implantation procedures: A comparison study of intracardiac and surface signals with an electrophysiology recording system.
Heart Rhythm
December 2024
Electrophysiology Unit, Cardiovascular Division, Hospital del Mar, Barcelona, Spain; Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Background: Left bundle branch area pacing (LBBAP) needs confirmation of left conduction system capture assessed by testing of different electrical parameters. Guidelines recommend the use of an electrophysiology recording system (EP-RS) to guide conduction system pacing procedures. However, some experienced centers perform LBBAP procedures without an EP-RS.
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