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Correction: The role of the SOX2 gene in cervical cancer: focus on ferroptosis and construction of a predictive model.
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The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, 315000, China.
Smoking-associated electrocardiographic abnormalities predict cardiovascular mortality.
Sci Rep
December 2024
Department of Physiology, School of Medicine, University of Louisville, Louisville, KY, USA.
Background -Smoking is associated with arrhythmia and sudden cardiac death, but the biological mechanisms remain unclear. In electrocardiogram (ECG) recordings abnormal durations of ventricular repolarization (QT interval), atrial depolarization (P wave), and atrioventricular depolarization (PR interval and segment), predict cardiac arrhythmia and mortality. Previous analyses of the National Health and Nutrition Examination Survey (NHANES) database for associations between smoking and ECG abnormalities were incomplete.
View Article and Find Full Text PDFDevelopment and validation of a nomogram model to predict the risk of strangulated intestinal obstruction.
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Department of Emergency Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, PR China.
To develop and validate a nomogram model for discriminating simple intestinal obstruction and strangulated intestinal obstruction, thus providing objective evidence for clinical decision-making. Following pre-established inclusion and exclusion criteria, a retrospective analysis was conducted on the clinical data of 560 patients diagnosed with intestinal obstruction who were admitted to the Emergency Surgery Department of the First Affiliated Hospital of Anhui Medical University between January 1, 2020, and December 31, 2022. The data was subsequently split into a training cohort (n = 393) and a validation cohort (n = 167) using a 7:3 ratio.
View Article and Find Full Text PDFA dual dimensional optimization strategy for automatic osteotomy preoperative planning in congenital radioulnar synostosis.
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Department of Hand Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Congenital radioulnar synostosis (CRUS) presents a complex forearm deformity, requiring precise osteotomy planning for anatomical restoration. This study proposes an automatic osteotomy preoperative planning method for forearms with CRUS. Proximal forearm bones are first aligned with the template forearm and then a dual dimensional optimization (DDO) strategy is used to optimize the spatial transformation parameters of the distal fragment.
View Article and Find Full Text PDFDiagnostic Accuracy of Novel Protein Biomarkers in Saliva to Detect Periodontitis Using Untargeted 'SWATH' Mass Spectrometry.
J Clin Periodontol
December 2024
Oral Sciences Research Group, Special Needs Unit, Department of Surgery and Medical-Surgical Specialties, School of Medicine and Dentistry, Universidade de Santiago de Compostela, Health Research Institute of Santiago (IDIS), Santiago de Compostela, Spain.
Aim: To discover new salivary biomarkers to diagnose periodontitis and evaluate the impact of age and smoking on predictive capacity.
Material And Methods: Saliva samples were collected from 44 healthy periodontal individuals and 41 with periodontitis. Samples were analysed by sequential window acquisition of all theoretical mass spectra (SWATH-MS), and proteins were identified by employing the UniProt database.
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