AI Article Synopsis
- The study aimed to determine if individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and a family history of the condition differ from those without such history.
- A total of 400 ME/CFS patients were examined alongside a control group of patients with multiple sclerosis and post-polio syndrome, revealing significant familial links to ME/CFS.
- Results showed that 18% of ME/CFS patients had family histories of the condition compared to only 3.9% in the control group and highlighted a correlation between family history and gastrointestinal symptoms in ME/CFS patients.
Article Abstract
Aim: It is unclear if individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with family histories of ME/CFS differ from those with ME/CFS without this family history. To explore this issue, quantitative data from patients with ME/CFS and controls were collected, and we examined those with and without family histories of ME/CFS.
Methods: The samples included 400 patients with ME/CFS, and a non-ME/CFS chronic illness control group of 241 patients with multiple sclerosis (MS) and 173 with post-polio syndrome (PPS).
Results: Confirming findings from prior studies, those with ME/CFS were more likely to have family members with ME/CFS than controls. We found family histories of ME/CFS were significantly higher (18%) among the ME/CFS group than the non-ME/CFS controls (3.9%). In addition, patients with ME/CFS who had family histories of ME/CFS were more likely to have gastrointestinal symptoms than those with ME/CFS without those family histories.
Conclusions: Given the recent reports of gastrointestinal difficulties among those with ME/CFS, our findings might represent one predisposing factor for the emergence of ME/CFS.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537498 | PMC |
| http://dx.doi.org/10.37349/emed.2024.00215 | DOI Listing |
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