User-friendly rehabilitation exercise devices can enhance health and quality of life through the convergence of information communication and medical technology. The development of rehabilitation exercise devices accessible to individuals with disabilities is important. We aimed to investigate the convenience, safety, and effectiveness of the developed rehabilitation exercise device for individuals with disabilities. A usability evaluation of the developed rehabilitation exercise device was conducted with five rehabilitation exercise experts and six athletes with disabilities using a questionnaire, the reliability of the revised questionnaire was =0.87. Qualitative analysis was conducted using semistructured interviews following the testing of the upper limb rehabilitation exercise device by the two user groups. In the usability evaluation survey of the developed rehabilitation exercise device, the results were very positive, with an overall score of 4.25 out of 5. The highest score was assigned to the convenience of the device, followed by the effectiveness of the exercise and the safety of the device. The developed rehabilitation exercise device allows for three types of strength improvement exercises, including isometric, isokinetic, and isotonic exercises, all within a single device. Given that it is constructed with a wire system, it can be adapted to various exercise methods, depending on the type of disability. The device can be used by both nondisabled and disabled individuals, allowing for various exercise methods. The evaluation results indicate that the proposed device is highly versatile and practical.
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http://dx.doi.org/10.12965/jer.2448410.205 | DOI Listing |
J Hand Ther
January 2025
Goztepe Prof Dr Suleyman Yalcin City Hospital, Department of Neurology, İstanbul, Turkey; İstanbul Medeniyet University, Faculty of Medicine, İstanbul, Turkey.
Background: Intraneural edema is an important factor in the pathophysiology of carpal tunnel syndrome (CTS). Manual Lymphatic Drainage (MLD) is a manual treatment widely used to treat edema in a variety of conditions.
Purpose: This study aimed to evaluate the effect of MLD on intraneural edema of the median nerve in CTS patients, as well as its impact on symptom severity and hand function.
J Hand Ther
January 2025
Konya Beyhekim Training and Research Hospital, Physical Medicine and Rehabilitation Clinic, Konya, Turkey.
Background: The effect of conservative treatments on sleep quality in carpal tunnel syndrome is unclear.
Purpose: Comparing the effect of splinting and kinesiotaping in carpal tunnel syndrome on functional status, pain, grip strength, nerve cross-sectional area and sleep quality.
Study Design: Randomized controlled study.
Clin Nutr
December 2024
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan.
Background & Aims: In older patients undergoing cardiac surgery, physical function is a critical determinant of postoperative outcomes. Beta-hydroxy-beta-methylbutyrate (HMB) supplementation has been shown to promote muscle protein anabolism and inhibit catabolism, thereby preventing muscle weakness. However, its efficacy in older patients undergoing cardiac surgery remains unknown.
View Article and Find Full Text PDFBioorg Chem
December 2024
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar, Punjab 160 062, India; School of Chemical Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata, West Bengal 700 032, India. Electronic address:
Tuberculosis (TB) remains a global health challenge, claiming numerous lives each year, despite recent advancements in drug discovery and treatment strategies. Current TB treatment typically involves long-duration chemotherapy regimens that are often accompanied by adverse effects. The introduction of new anti-TB drugs, such as Bedaquiline, Delamanid, and Pretomanid, offers hope for more effective treatment, although challenges persist keeping the quest to find new anti-TB chemotypes an incessant exercise of medicinal chemists.
View Article and Find Full Text PDFPulmonology
December 2025
Laboratory of Experimental Therapeutics, LIM-20, Department of Clinical Medicine, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Background: Chronic obstructive pulmonary disease (COPD) induces an imbalance in T helper (Th) 17/regulatory T (Treg) cells that contributes to of the dysregulation of inflammation. Exercise training can modulate the immune response in healthy subjects.
Objective: We aimed to evaluate the effects of exercise training on Th17/Treg responses and the differentiation of Treg phenotypes in individuals with COPD.
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