AI Article Synopsis

  • - The study explores the effectiveness of a second acquisition during contrast-enhanced MR angiography (CE-MRA) to improve the evaluation of blood flow in patients with past internal carotid artery occlusions.
  • - Using a retrospective analysis, researchers compared CE-MRA results with MR perfusion data and digital subtraction angiography (DSA) to assess discrepancies in occlusion locations and collateral blood flow.
  • - Findings indicate that 28.5% of patients displayed a false appearance of occlusion in the early phase of CE-MRA, suggesting that the second acquisition could reveal important details missed initially, particularly regarding collateral circulation.

Article Abstract

Background: Double-concentration magnetic resonance imaging (MRI) contrast agents are frequently used in contrast-enhanced MR angiography (CE-MRA) of the head and neck. To avoid mistiming the peak concentration of intraluminal contrast (due to shorter duration of peak), a second acquisition is sometimes performed.

Purpose: To evaluate additional information from the second acquisition of CE-MRA and compare the collateral scoring to the hypoperfusion index obtained on MR perfusion, and to investigate presence of pseudo-occlusion using the second phase of CE-MRA.

Material And Methods: A retrospective study was conducted. CE-MRA of the brain/neck, dynamic susceptibility contrast (DSC) MR perfusion scan (in majority) and subsequent digital subtraction angiography (DSA) were evaluated in patients with previous acute internal carotid artery (ICA)/middle cerebral artery (MCA) occlusion. Evaluation of CE-MRA/MR perfusion and DSA was performed by three experienced neuroradiologists and one neurointerventionist, respectively.

Results: The site of ICA occlusion was seen to be distal to the site noted on early arterial phase (pseudo-occlusion of ICA) in 28.5% of patients. A significant negative correlation was seen between a higher HIR and collateral score.

Conclusion: Evaluation of second phase CE-MRA can provide valuable information that may be otherwise lost if only the early arterial phase is evaluated.

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Source
http://dx.doi.org/10.1177/02841851241290728DOI Listing

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