Purpose: We investigated the relationship between oral frailty (OFr) and falls among long-term care residents.
Methods: Residents (N = 254, mean age 84 y, 79% women) participated in this longitudinal cohort study in 2018-2021. OFr was defined by six signs. Demographics, diagnoses, and medications were retrieved from the medical records. Frailty phenotype, sarcopenia and disability were assessed. Number of falls was collected from medical records over 12 months following baseline assessment.
Results: Of participants, 35% fell during follow-up. Of the fallers, 28% were bedridden or needed a wheelchair; among non-fallers, this figure was 73%. In logistic regression analysis after adjusting for age, sex, BMI, stroke, dementia, diabetes, coronary heart disease, number of medications, mobility, walking speed and sarcopenia, OFr did not predict falls (OR for severe OFr 0.13 (95% CI 0.01-1.27). Male sex predicted falls.
Conclusions: No association was found between severe OFr and falls over a 12-month follow-up.
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http://dx.doi.org/10.1007/s41999-024-01088-6 | DOI Listing |
Alzheimers Dement
December 2024
National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Background: In Japan, effective interventions to prevent low nutrition in older people with oral frailty have not been well established. This post-hoc sub-group analysis of the Japan-multimodal intervention trial for the prevention of dementia (J-MINT) aimed to examine the efficacy of the multidomain intervention in older adults with and without oral frailty.
Methods: J-MINT was an 18-month randomized controlled trial in which participants aged 65-85 years with mild cognitive impairment were randomized to a multimodal intervention group (physical exercise, nutrition counseling, cognitive training, and vascular risk factor management) and a control group.
J Gen Fam Med
January 2025
Department of Primary Care and Medical Education, Institute of Medicine University of Tsukuba Ibaraki Japan.
Background: Chronic periodontal disease primarily causes tooth loss and oral frailty and is linked to chronic conditions such as diabetes mellitus. However, its progression and broader studies on chronic diseases have not been well explored. This study aimed to investigate this association using claims data.
View Article and Find Full Text PDFJ Trauma Acute Care Surg
January 2025
From the Spencer Fox Eccles School of Medicine (D.G., J.A.), Department of Neurosurgery (D.B., M.T.B., S.T.M., R.G.), Department of Surgery (S.L., J.C., M.M., T.E.), Division of Geriatrics and Department of Internal Medicine (M.P.), University of Utah, Salt Lake City, Utah; and Bowers Neurosurgical Frailty and Outcomes Data Science Lab (C.A.B.), Flint, Michigan.
Background: Preinjury antithrombotic (AT) use is associated with worse outcomes for geriatric (65 years or older) patients with traumatic brain injury (TBI). Previous studies have found that use of AT outside established guidelines is widespread in TBI patients.
Methods: In this single-center retrospective cross-sectional study, we examined inappropriate AT use among geriatric patients presenting with traumatic intracranial hemorrhage.
Br J Haematol
January 2025
Service d'hématologie, Centre Hospitalo-Universitaire, Nantes, France.
Most transplant-ineligible patients present with multiple myeloma (MM) refractory to lenalidomide and/or anti-CD38 monoclonal antibody at first relapse and represent a difficult-to-treat population. The Intergroupe Francophone du Myélome phase 2 study iberdomide, ixazomib and dexamethasone (I2D) evaluated the oral triplet iberdomide, ixazomib and dexamethasone in MM patients aged ≥70 years at first relapse (NCT04998786). Seventy patients were enrolled to receive iberdomide (1.
View Article and Find Full Text PDFJ Prosthodont Res
January 2025
Department of Prosthodontics, Gerontology and Oral Rehabilitation, Osaka University Graduate School of Dentistry, Suita, Japan.
Purpose: Although the association between oral health and physical frailty is well established, psychological frailty has not been investigated. Therefore, this prospective cohort study was conducted to examine the association between masticatory performance and psychological frailty in older community-dwelling Japanese individuals.
Methods: The participants included 498 older adults who completed baseline and 3- and 6-year follow-up surveys.
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