AI Article Synopsis
- - Three new compounds related to monacolin were discovered from red yeast rice extract: monacolin V, 6-hydroxyl monacolin P, and 3-keto monacolin S.
- - The structures of these compounds were identified using high-resolution mass spectrometry (HRESIMS) and nuclear magnetic resonance (NMR) techniques.
- - This research marks the first complete assignment of NMR data for the new compounds 6-hydroxyl monacolin P and 3-keto monacolin S.
Article Abstract
One new monacolin analog, monacolin V (1), together with two new monacolin-like natural products, 6-hydroxyl monacolin P (2) and 3-keto monacolin S (3), were isolated from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were identified by HRESIMS and NMR experiments, and the complete assignments of H and C NMR data for three compounds were obtained by the aid of HSQC, HMBC, H-H COSY, and NOESY data. This is the first time that the NMR data of compounds 2 and 3 have been fully assigned.
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| http://dx.doi.org/10.1002/mrc.5489 | DOI Listing |
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