AI Article Synopsis
- Traditional methods for studying sperm and embryos focused on microscopy to evaluate their structure and movement.
- OMICS technologies, particularly transcriptomics, are now being utilized to analyze fertility markers at cellular and molecular levels with greater sensitivity.
- This review highlights the significance of specific genes in sperm function and fertilization, and also discusses the role of shared miRNAs in sperm, oocytes, and early embryos during development.
Article Abstract
Traditionally, sperm and embryos were studied using microscopy to assess morphology and motility. However, OMICS technologies, especially transcriptomic analysis, are now being used to screen the molecular dynamics of fertility markers at cellular and molecular levels, with high sensitivity. Transcriptomics is the study of the transcriptome - RNA transcripts produced by the genome - using high-throughput methods to understand how the RNAs are expressed. In this review, we have discussed gene contributions to sperm structure and function and their role in fertilization and early embryo development. Further, we identified miRNAs shared by sperm, oocytes, and early embryos and their roles in fertilization and early embryo development.
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| http://dx.doi.org/10.1016/j.anireprosci.2024.107630 | DOI Listing |
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