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Porokeratoses-A Rare Group of Dermatoses.
Medicina (Kaunas)
November 2024
Department of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, 35010 Rzeszow, Poland.
Porokeratoses represent a rare group of skin diseases characterized by abnormal keratinization. The condition may have a genetic background and can be triggered by environmental factors, including UV exposure and infections. Several clinical variants of porokeratosis can be distinguished, including Mibelli's porokeratosis, disseminated superficial actinic porokeratosis, superficial disseminated porokeratosis, and porokeratosis palmaris plantaris et disseminata.
View Article and Find Full Text PDFSuccessful treatment of porokeratosis of Mibelli with pathogenesis-directed treatment of topical cholesterol-lovastatin.
Pediatr Dermatol
January 2024
Division of Pediatric Dermatology, Department of Pediatrics, University of Texas at Austin-Dell Medical School, Austin, Texas, USA.
Treatment of Mibelli angiokeratoma with pulsed dye laser: a retrospective study of 21 cases.
Lasers Med Sci
November 2024
Hospital for Skin Diseases, Shandong First Medical University, Shandong, China.
Bacterial shift and resistance pattern in pancreatic head resections after selective decontamination of the digestive tract - a propensity score-matched analysis.
J Gastrointest Surg
November 2024
Department of Visceral, Thoracic, and Vascular Surgery, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; National Center for Tumor Diseases, Dresden, Germany: German Cancer Research Center, Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; and Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Germany. Electronic address:
Background: Pancreatic head resection is associated with postoperative morbidity, primarily because of infectious complications. The microbiota in these infections is crucial, and selective decontamination of the digestive tract (SDD) aims to mitigate this risk by targeting pathogenic organisms while preserving beneficial flora. This study aimed to determine the effect of SDD on bacterial shifts and resistance patterns in pancreatic head resection.
View Article and Find Full Text PDFPorokeratosis of Mibelli Treated With Topical 2% Lovastatin/2% Cholesterol Ointment.
Cureus
July 2024
Department of Dermatology, Poznan University of Medical Sciences, Poznan, POL.
Article Synopsis
- Porokeratosis is a skin condition caused by disruptions in the isoprenoid pathway, leading to lesions made up of parakeratotic cells, often linked to genetic mutations impacting cholesterol synthesis.
- A case study of a 56-year-old male with Mibelli porokeratosis showed that traditional treatments were ineffective for a persistent finger lesion that didn’t heal for two years.
- The introduction of a topical ointment containing 2% lovastatin and 2% cholesterol resulted in significant improvement after nine months, suggesting promising potential for this treatment approach in managing porokeratosis.
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