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Overexpression of caused by tandem amplification contributed to ceftazidime/avibactam resistance in hypervirulent and carbapenem-resistant . | LitMetric

We identified a novel ceftazidime/avibactam (CAZ/AVI) resistance mechanism in endemic sequence type 11 hypervirulent and carbapenem-resistant isolated from a patient who had not been exposed CAZ/AVI. Overexpression of caused by tandem gene amplification contributed to CAZ/AVI resistance instead of the carriage of . Enhanced genomic surveillance is essential to identify emerging variants.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11565672PMC
http://dx.doi.org/10.1080/22221751.2024.2426481DOI Listing

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