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Multifaceted Immunomodulatory Nanocomplexes Target Neutrophilic-ROS Inflammation in Acute Lung Injury.
Adv Sci (Weinh)
December 2024
Department of Critical Care Medicine and Emergency, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China.
The sepsis-induced acute lung injury (ALI) still represents one of the leading causes of death in critically ill patients, underscoring the need for novel therapies. Excessive activation of immune cells and damage of reactive oxygen species (ROS) are the main factors that exacerbate lung injury. Here, the multifaceted immunomodulatory nanocomplexes targeting the proinflammatory neutrophilic activation and ROS damage are established.
View Article and Find Full Text PDFHigh Performance KNN-Based Macro Fiber Composites for Human Motion Monitoring Applications.
Small
December 2024
College of Materials Science and Engineering, Sichuan University, Chengdu, 610064, China.
Piezoelectric materials are increasingly used in portable smart electronics and Internet of Things sensors. Among them, piezoelectric macro fiber composites (MFCs) have attracted much attention due to their architectural simplicity, scalability, and high-power density. However, most MFCs currently use toxic lead-based piezoelectric materials, hindering their applications for bio-friendly intelligent electronics.
View Article and Find Full Text PDFElevated neurofilament light chain associated with cobalt/chromium metal neurotoxicity in a patient with a failed hip implant.
Clin Chim Acta
December 2024
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:
Background: It is known that the heavy metals cobalt and chromium are associated with neurotoxicity. Chromium (Cr) and Cobalt (Co) are both components of metal-on-metal (MoM) implants which can be degraded/fragmented and released into the bloodstream. Neurofilament Light Chain (NfL) is a neuron-specific protein that increases in serum following axonal damage.
View Article and Find Full Text PDFFibrous MoS/BiS/BiFeO ternary heterojunction boosts piezoelectric photocatalytic performance.
J Colloid Interface Sci
December 2024
Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, Shenzhen Key Laboratory of Special Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, PR China. Electronic address:
Photocatalytic removal of antibiotic such as ciprofloxacin from polluted water is of great value for eco-environment protection. To further enhance the piezoelectric effect in photocatalysis, we designed and synthesized a ternary heterojunction piezoelectric photocatalyst through uniformly loading MoS nanosheets onto BiFeO (BFO) nanofibers, namely MoS/BiS/BFO. Piezoresponse force microscopy and Kelvin probe force microscopy demonstrated its enhanced piezoelectric properties, showing a maximum amplitude displacement of 395.
View Article and Find Full Text PDFA ceramic microbridge microfluidic chip to study osteogenic differentiation of mesenchymal stem cells in bioactive ceramic immune microenvironment.
Bioact Mater
March 2025
College of Biomedical Engineering, Sichuan University, Chengdu, Sichuan, 610064, China.
Bioactive ceramics have been used in bone tissue repair and regeneration. However, because of the complex in vivo osteogenesis process, long cycle, and difficulty of accurately tracking, the mechanism of interaction between materials and cells has yet to be fully understood, hindering its development. The ceramic microbridge microfluidic chip system may solve the problem and provide an in vitro method to simulate the microenvironment in vivo.
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