Background: Behavioural problems in individuals with intellectual disabilities have a negative impact on them. Limited assessment measures exist in Spain. This study aimed to validate the Behavior Problems Inventory-Short Form (BPI-S) in the Spanish population by examining its psychometric properties and factorial structures.
Method: This study included 458 individuals with intellectual disabilities evaluated by 137 professionals. The validity and reliability of the scale were examined.
Results: The validity of the measurement tool confirmed a three-factor model. Significant correlations were observed between problem behaviours and maladaptive behaviour indicators, with negative associations found between problem behaviours and adaptive behaviour scores.
Conclusions: The Spanish version of the BPI-S demonstrated good internal consistency and convergent and discriminant validities. The most common behaviours were identified, and the scale was refined to 28 items. The three-factor model showed an acceptable fit. Further research is required to establish clinical norms and explore the factorial structures.
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http://dx.doi.org/10.1111/jar.13312 | DOI Listing |
Knowledge of the natural history of deficiency disorder (CDD) is limited to the results of cross-sectional analysis of largely pediatric cohorts. Assessment of outcomes in adulthood is critical for clinical decision-making and future precision medicine approaches but is challenging because of the diagnostic gap and duration of follow-up that would be required for prospective studies. We aimed to delineate the natural history retrospectively from adulthood.
View Article and Find Full Text PDFAutism Res
January 2025
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Catatonia is a highly morbid psychomotor and affective disorder, which can affect autistic individuals with and without intellectual disability. Catatonic symptoms are treatable with pharmacotherapy and electroconvulsive therapy, but the longitudinal effectiveness of these treatments in autistic individuals has not been described. We conducted a prospective observational cohort study of patients with autism and co-morbid catatonia who received outpatient care in a specialized outpatient clinic from July 1, 2021 to May 31, 2024.
View Article and Find Full Text PDFCell Mol Biol Lett
January 2025
University Cote d'Azur, Inserm, C3M, Nice, France.
Vacuolization of hematopoietic precursors cells is a common future of several otherwise non-related clinical settings such as VEXAS, Chediak-Higashi syndrome and Danon disease. Although these disorders have a priori nothing to do with one other from a clinical point of view, all share abnormal vacuolization in different cell types including cells of the erythroid/myeloid lineage that is likely the consequence of moderate to drastic dysfunctions in the ubiquitin proteasome system and/or the endo-lysosomal pathway. Indeed, the genes affected in these three diseases UBA1, LYST or LAMP2 are known to be direct or indirect regulators of lysosome trafficking and function and/or of different modes of autophagy.
View Article and Find Full Text PDFRinsho Shinkeigaku
January 2025
Department of Neurology, The University of Tokyo Hospital.
The patient was a 33-year-old woman with no family history of a similar disorder. At one year of age, she exhibited scoliosis and respiratory failure, necessitating a tracheostomy performed at 5 years of age (1990s). During that time, the patient was provisionally diagnosed with "non-Fukuyama congenital muscular dystrophy" via muscle biopsy.
View Article and Find Full Text PDFRes Dev Disabil
January 2025
Department of Psychology and Cognitive Science, University of Trento, Rovereto, Italy. Electronic address:
Quality of Life (QoL) is a crucial concept that pertains to an individual's perception of their position in life. In the context of developmental disabilities, QoL is pivotal for improving evidence-based practices, providing support and organizing services for individuals, thereby enabling them to achieve their potential with dignity and equality. Despite its importance, QoL has often not been the primary focus in many studies on developmental disabilities and remains less developed compared to other research areas.
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