Maxillofacial injuries are often seen in patients with multiple injury. The principal problem is control of the airway and treatment of shock. Surgical procedure and anaesthetic management have to consider the priority of stabilization of vital functions. Injury and shock lead to alterations in circulation, lung function, and electrolyte balances, which the anaesthesist has to bear in mind. Orotracheal intubation should be performed primarily, the definite control of the airway depends on the degree of trauma and the expected course. If the patient requires longterm ventilation a tracheostomy is indicated during early treatment.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes.
Sci Adv
January 2025
Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
Protein homeostasis is crucial for maintaining cardiomyocyte (CM) function. Disruption of proteostasis results in accumulation of protein aggregates causing cardiac pathologies such as hypertrophy, dilated cardiomyopathy (DCM), and heart failure. Here, we identify ubiquitin-specific peptidase 5 (USP5) as a critical determinant of protein quality control (PQC) in CM.
View Article and Find Full Text PDFMASP1 modulation as a novel therapeutic target in severe pediatric pertussis: insights from a multi-omics approach.
Infect Immun
January 2025
Department of Pediatrics, Beijing Ditan Hospital Affiliated to Capital Medical University, Beijing, China.
Pertussis, a severe infectious disease in children, has become increasingly prominent in recent years. This study aims to investigate the role of the MASP1 protein in severe pertussis in children through multi-omics analysis, providing a theoretical basis for the development of novel therapeutic strategies. The study retrieved macro-genome and 16S rRNA data of pediatric pertussis from public databases to analyze microbial diversity and specific flora abundance, conducting pathway functional enrichment analysis.
View Article and Find Full Text PDFSex hormones and allergies: exploring the gender differences in immune responses.
Front Allergy
January 2025
Research Institute of Biomedical Sciences, University Center of Health Sciences, University of Guadalajara, Guadalajara, Mexico.
Allergies are closely associated with sex-related hormonal variations that influence immune function, leading to distinct symptom profiles. Similar sex-based differences are observed in other immune disorders, such as autoimmune diseases. In allergies, women exhibit a higher prevalence of atopic conditions, such as allergic asthma and eczema, in comparison to men.
View Article and Find Full Text PDFVitronectin regulates lung tissue remodeling and emphysema in chronic obstructive pulmonary disease.
Mol Ther
January 2025
Immune Health, Hunter Medical Research Institute and The University of Newcastle, Newcastle, New South Wales, Australia; Centre for Inflammation, Centenary Institute and University of Technology Sydney, School of Life Sciences, Faculty of Science, Sydney, New South Wales, Australia. Electronic address:
Vitronectin (VTN) is an important extracellular matrix protein in tissue remodeling, but its role in COPD is unknown. We show that VTN regulates tissue remodeling through urokinase plasminogen activator (uPA) signaling pathway in COPD. In human COPD airways and bronchoepithelial cells and the airways of mice with cigarette smoke (CS)-induced experimental COPD, VTN protein was not changed, but downstream uPA signaling was altered (increased plasminogen activator inhibitor-1, uPAR) that induced collagen and airway remodeling.
View Article and Find Full Text PDFThe effect of two different surgical positions on pulmonary functions ın laparoscopic sleeve gastrectomies: reverse Trendelenburg vs beach chair.
Surg Endosc
January 2025
Department of Anesthesiology and Reanimation, Faculty of Medicine, Istınye University Medicalpark Gaziosmanpasa Hospital, Istanbul, Turkey.
Background: The aim of our study is to compare the effect of the 30° reverse Trendelenburg position combined with the beach chair position on respiratory parameters in laparoscopic sleeve gastrectomy (LSG) with the 30° reverse Trendelenburg position alone.
Material And Method: Fifty patients with body mass index > 30 were included in the study. The patients were divided into two groups; in the control group, the standard 30° reverse Trendelenburg.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!