What intrinsic factors affect the central corneal thickness?

Ophthalmic Physiol Opt

Physics Centre of Minho and Porto Universities (CF-UM-UP), School of Sciences, University of Minho, Braga, Portugal.

Published: January 2025

AI Article Synopsis

  • The cornea is essential for protecting the eye, and central corneal thickness (CCT) measures its thickness from the front to the back.
  • CCT is crucial for accurate intraocular pressure measurements, assessing corneal health, and planning refractive surgeries.
  • Understanding the various factors that affect CCT can improve diagnostic and treatment approaches in eye care.

Article Abstract

The cornea is one of the tissues responsible for covering and protecting the inner structures of the eye. Central corneal thickness (CCT) is defined as the distance between the anterior epithelial surface and the posterior surface of the endothelial layer. This parameter plays a very important role regarding intraocular pressure (IOP) measurement, evaluation of corneal uniformity, selection of a suitable technique for corneal refractive surgery and the planning of surgical procedures to overcome corneal disease. This comprehensive review elucidates the multifaceted factors influencing the central corneal thickness. Recognising the impact of these factors not only enhances our understanding of corneal dynamics but also contributes significantly to the refinement of diagnostic and therapeutic strategies in ophthalmology.

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Source
http://dx.doi.org/10.1111/opo.13414DOI Listing

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