A silver-mediated cascade trifluoromethylthiolation/cyclization of unactivated alkenes has been investigated. This strategy employs AgSCF as the trifluoromethylthiolating reagent to obtain a variety of useful trifluoromethylthiolated tricyclic imidazol derivatives in reasonable yields. Preliminary mechanistic studies indicate that the present reaction takes place a radical process. This method is distinguished by its atom economy, wide functional group compatibility, operational simplicity and product diversity.
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| http://dx.doi.org/10.1039/d4ob01582g | DOI Listing |
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