AI Article Synopsis
- The PRIDE database is a premier repository for mass spectrometry-based proteomics data and plays a key role in the ProteomeXchange consortium, facilitating research sharing.
- Over the past three years, PRIDE has made significant advancements, including a new file transfer protocol and an automatic dataset validation process, resulting in approximately 534 datasets submitted monthly.
- Recent innovations include the introduction of a PRIDE chatbot for user support and enhanced efforts to integrate high-quality data with resources like UniProt and Ensembl.
Article Abstract
The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world's leading mass spectrometry (MS)-based proteomics data repository and one of the founding members of the ProteomeXchange consortium. This manuscript summarizes the developments in PRIDE resources and related tools for the last three years. The number of submitted datasets to PRIDE Archive (the archival component of PRIDE) has reached on average around 534 datasets per month. This has been possible thanks to continuous improvements in infrastructure such as a new file transfer protocol for very large datasets (Globus), a new data resubmission pipeline and an automatic dataset validation process. Additionally, we will highlight novel activities such as the availability of the PRIDE chatbot (based on the use of open-source Large Language Models), and our work to improve support for MS crosslinking datasets. Furthermore, we will describe how we have increased our efforts to reuse, reanalyze and disseminate high-quality proteomics data into added-value resources such as UniProt, Ensembl and Expression Atlas.
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| http://dx.doi.org/10.1093/nar/gkae1011 | DOI Listing |
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