AI Article Synopsis
- * Symptoms and complications may differ between genders, with men experiencing more dissection and aneurysms than women.
- * Diagnosis requires careful evaluation and imaging, while treatment typically involves monitoring and antiplatelet therapy; ongoing research is focused on understanding the genetic aspects of FMD.
Article Abstract
Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory vascular disease that was once underrecognized and is significantly more prevalent in women than men. Although it most commonly affects the renal and extracranial carotid arteries, FMD can affect any vascular bed. Complications of FMD can include hypertension, dissection, and stroke. Presentation may vary between the sexes, with male patients having an increased frequency of arterial dissection and aneurysms compared with female patients. Diagnosis requires a high index of suspicion by the treating physician. Several imaging studies can assist with diagnosis, and treatment focuses on the monitoring of affected vessels and intervention only as needed. Antiplatelet therapy for prevention of thrombotic complications is recommended. Studies are still underway to examine the genetic underpinnings of FMD pathophysiology and to evaluate the underlying mechanism of this disease that affects more female than male patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526498 | PMC |
| http://dx.doi.org/10.15420/usc.2023.03 | DOI Listing |
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- Renal artery stenosis (RAS) is a condition where the renal artery is narrowed by 60% or more, most commonly due to atherosclerotic plaques, affecting 5-10% of the population; rare causes include fibromuscular dysplasia and vasculitis.
- The standard diagnostic method for RAS is digital subtraction angiography (DSA), but other imaging techniques like Doppler ultrasonography and CT angiography are also important.
- Treatment typically involves percutaneous transluminal angioplasty (PTA), and a case study highlights a 19-year-old patient who benefitted from using a paclitaxel-coated balloon to restore renal artery function and reduce hypertension.
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