AI Article Synopsis
- The rise of plastic pollution is a serious global issue that poses both environmental and health risks, particularly due to microplastics (MPs) and nanoplastics (NPs) released from degrading plastics.
- Humans are regularly exposed to these tiny particles through ingestion, inhalation, and skin contact, leading to potential health impacts, especially in vital systems like cardiovascular, nervous, reproductive, and digestive systems.
- This review compiles the latest research on the toxic effects of micro- and nanoplastics in human health, aiming to increase awareness and support the development of strategies to combat this ongoing plastic crisis.
Article Abstract
The escalation of plastic pollution represents a global environmental and health problem. Important toxic effects have been attributed to the increasing diffusion of microplastics (MPs) and nanoplastics (NPs) derived from the degradation of plastics. These particles have been ubiquitously observed in the environment, with humans being continuously exposed via ingestion, inhalation and skin contact. Nonetheless, the cellular homeostasis imbalance induced by micro- and nano- plastics (MNPs) in human health has been only recently shown, while most evidence and molecular mechanisms derived from studies and models. To date, the majority of available results testified the accumulation of MNPs in the cardiovascular, nervous, reproductive and digestive systems, and recently clear evidence about cardiovascular toxic effects of MNPs has been provided in humans. In this context, this review aims to provide a comprehensive update about the most recent studies reporting the effects of MNPs in different models, focusing on the available evidence in the main areas of study related to human health. Hopefully, this review will contribute to raise awareness about the toxicity and oxidative alteration exerted by MNPs, supporting the elaboration of new strategies to counteract plastic pandemics.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528458 | PMC |
| http://dx.doi.org/10.7150/ijbs.99556 | DOI Listing |
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