AI Article Synopsis
- * The tumor identified was a sex cord-stromal (granulosa cell) tumor, and the heifer's sex chromosome type was confirmed to be XX, indicating an ovotesticular disorder of sexual development with female characteristics.
- * This case highlights that while disorders of sexual development are common in mammals, the occurrence of gonadal tumors in these conditions is infrequent and has not been previously documented in cattle.
Article Abstract
Development of gonadal tumors within an ovotestis is rare in mammals and this disturbance was not reported in cows. We report herein a gonadal stromal (granulosa cell) tumor in an ovotestis of a 15-month-old heifer from which the reproductive tract was obtained from a local slaughterhouse. Histopathological evaluation revealed that the gonads were ovotestis, but also a coincidental sex cordstromal (granulosa cell) tumor. The sex chromosome type was determined to be XX, suggesting an XX ovotesticular disorder of sexual development with uterus and a female phenotype. Key clinical message: Disorders of sexual development are common in mammals. Gonadal tumors in disorders of sexual development are rarely reported and have not been reported in cows.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486109 | PMC |
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