Paul Farmer, a distinguished physician and anthropologist known by many as a pioneer in global health endeavors, made a profound impact on the landscape of healthcare. Through his innovative approaches to healthcare delivery and his unwavering commitment to social justice and health equity, he changed the landscape of healthcare on a global scale. He was a Kolokotrones University Professor, Chair of the Department of Global Health and Social Medicine at Harvard Medical School, Chief of the Division of Global Health Equity at Brigham and Women's Hospital in Boston, Chancellor of the University of Global Health Equity in Rwanda, and Chief Strategist and Co-founder of Partners In Health (PIH). PIH is an international non-profit organization that embarked on research and healthcare advocacy initiatives, providing direct healthcare services for those in resource-limited communities worldwide. Farmer, through his development of innovative and heartfelt approaches to healthcare delivery and social justice medicine, exemplified how integrating community engagement and social determinants of health can lead to transformative healthcare solutions and ultimately improve patient experiences. This vignette explores Farmer's early life, educational journey, and major contributions to medicine and social justice in healthcare, emphasizing the enduring impact of his work on public health and future generations of medical professionals.
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http://dx.doi.org/10.7759/cureus.70724 | DOI Listing |
BioDrugs
January 2025
Orsay-Vallée Campus, Paris-Saclay University, Gif-sur-Yvette, France.
Liver cancer poses a global health challenge with limited therapeutic options. Notably, the limited success of current therapies in patients with primary liver cancers (PLCs) may be attributed to the high heterogeneity of both hepatocellular carcinoma (HCCs) and intrahepatic cholangiocarcinoma (iCCAs). This heterogeneity evolves over time as tumor-initiating stem cells, or cancer stem cells (CSCs), undergo (epi)genetic alterations or encounter microenvironmental changes within the tumor microenvironment.
View Article and Find Full Text PDFCardiovasc Toxicol
January 2025
RAK College of Medical Sciences, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.
The rapid development and deployment of mRNA and non-mRNA COVID-19 vaccines have played a pivotal role in mitigating the global pandemic. Despite their success in reducing severe disease outcomes, emerging concerns about cardiovascular complications have raised questions regarding their safety. This systematic review critically evaluates the evidence on the cardiovascular effects of COVID-19 vaccines, assessing both their protective and adverse impacts, while considering the challenges posed by the limited availability of randomized controlled trial (RCT) data on these rare adverse events.
View Article and Find Full Text PDFClin Exp Nephrol
January 2025
Internal Medicine Department, El Qabbary General Hospital, Ministry of Health, Alexandria, Egypt.
Background: Oral nutritional supplements (ONS) are commonly prescribed to provide protein and energy to hemodialysis (HD) patients. There is a debate about the appropriate timing to administer ONS. We aimed to study the effect of different timings of ONS on variable outcomes in HD patients.
View Article and Find Full Text PDFRheumatol Int
January 2025
School of Medicine, The University of Western Australia, 35 Stirling Highway, Perth, WA, 6009, Australia.
This study aims to review the literature and estimate the global pooled prevalence of interstitial lung disease among patients with rheumatoid arthritis (RA-ILD). The influence of risk factors like geography, socioeconomic status, smoking and DMARD use will be explored. A systematic review was performed according to the PRISMA and JBI guidelines.
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