Sebaceoma of the Eyelid Originating in a Meibomian Gland: A Rare Case and Literature Review.

Cureus

Department of General and Clinical Pathology, Forensic Medicine and Deontology, Medical University of Varna, Varna, BGR.

Published: October 2024

AI Article Synopsis

  • - Sebaceoma is a rare benign tumor with sebaceous gland characteristics, commonly found on the face, scalp, or trunk, and extremely seldom in the eyelid region.
  • - Only five cases of eyelid sebaceoma have been documented, with one case linked to a Meibomian gland, emphasizing the rarity of this condition.
  • - A recent case is reported involving a 64-year-old male with sebaceoma of the left lower eyelid margin, diagnosed through histopathological examination amidst challenges in distinguishing it from other skin lesions.

Article Abstract

Sebaceoma is an infrequently diagnosed benign neoplasm with sebaceous differentiation. This tumor usually presents in areas rich in sebaceous glands, such as the face, scalp, or trunk. The periocular tissues are an exceptionally uncommon site for sebaceoma, making sebaceoma of the eyelid an extremely rare entity. To our knowledge, only five cases of sebaceoma of the eyelid have been reported, with only one of these five originating in a Meibomian gland. Due to its rarity and the wide spectrum of skin lesions, sebaceoma is considered a diagnostically challenging lesion. When the diagnosis is uncertain, a biopsy followed by histopathological analysis should be performed to carefully differentiate sebaceoma from other eyelid tumors. Histopathologically, sebaceoma displays a wide range of patterns, from those seen in sebaceous adenoma to features that can be difficult to distinguish from sebaceous gland carcinoma. We report the case of a 64-year-old Caucasian male presenting with sebaceoma of a Meibomian gland of the left lower eyelid margin. The diagnosis of sebaceoma was made based on a routine histopathological examination.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528873PMC
http://dx.doi.org/10.7759/cureus.70686DOI Listing

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