AI Article Synopsis

  • Challenging adherence to positive airway pressure (PAP) therapy in patients with allergic rhinitis was highlighted in a case study of a 62-year-old male with obstructive sleep apnea (OSA) who struggled with PAP for ten years.
  • The combination of daily intranasal oxymetazoline and fluticasone significantly improved his tolerance and adherence to PAP therapy, unlike using fluticasone alone.
  • This approach may help enhance CPAP tolerance in patients with OSA and rhinitis, offering a promising area for future exploration to improve treatment adherence.

Article Abstract

Adherence to positive airway pressure (PAP) therapy is a challenge in patients with allergic rhinitis. We present a case of a 62-year-old male with OSA who had been struggling with PAP therapy for ten years. Intranasal fluticasone alone did not result in tolerance of PAP therapy. However, the combination of once- daily intranasal oxymetazoline with fluticasone led to significant improvement in tolerance and adherence to PAP therapy. While twice daily oxymetazoline alone has been associated with developing rhinitis medicamentosa, this side effect was not experienced by our patient. Some studies have shown that using intranasal oxymetazoline along with an intranasal steroid once daily for four weeks demonstrated improved effectiveness in relieving nasal symptoms with no development of rebound congestion or rhinitis medicamentosa. This strategy may be helpful in improving CPAP tolerance for patients with concurrent OSA and rhinitis, a potential area to explore in the future to improve PAP adherence.

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Source
http://dx.doi.org/10.5664/jcsm.11454DOI Listing

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