Current options for the prevention of postoperative intra-abdominal adhesions.

Asian J Surg

University of Defence, Faculty of Military Health Sciences, Department of Military Surgery, Hradec Kralove, Czech Republic; University Hospital and Charles University, Faculty of Medicine, Department of Surgery, Hradec Kralove, Czech Republic.

Published: October 2023

AI Article Synopsis

  • - Postoperative adhesions are a major problem after abdominal and pelvic surgeries, leading to complications that can arise soon after surgery or much later.
  • - These adhesions occur due to surgical trauma or infection, disrupting the normal healing process in the peritoneum, where there's an imbalance between fibrin build-up and break down.
  • - The paper reviews how postoperative adhesions develop and discusses different methods to potentially prevent them, using data from various medical research databases.

Article Abstract

Postoperative adhesions are the most common cause of morbidity after abdominal and pelvic surgery. The clinical manifestations of postoperative adhesions can manifest within a few weeks or even several years after the surgery. They result from peritoneal irritation caused by surgical trauma or intra-abdominal infection. Normal peritoneal healing relies on the balance between fibrin deposition and its degradation. In this paper-using information derived from the Medline, PubMed, and ScienceDirect databases-we briefly summarize the pathogenesis of postoperative intra-abdominal adhesions and various strategies for possible prevention.

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Source
http://dx.doi.org/10.1016/j.asjsur.2023.10.001DOI Listing

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