AI Article Synopsis
- The systematic review analyzed multiple studies to determine the effectiveness of the micronucleus assay for monitoring genetic damage in workers exposed to anesthetic gases.
- A total of 18 articles were included after thorough screening, with quality assessments rating 12 as strong, 3 as moderate, and 3 as weak.
- Overall, the findings suggest that exposure to anesthetic agents can lead to genetic damage, and the micronucleus assay is a reliable biomarker for detecting this damage in affected professionals.
Article Abstract
The present systematic review, through the analysis of several studies, focused on attempting to answer the following question: Is the micronucleus assay suitable for genetic biomonitoring of workers exposed to anesthetic gases? We conducted searches in PubMed, SCOPUS and Web of Science to identify eligible articles on December, 2023. After screening the manuscript, a total of 18 articles were included in the review. In the quality assessment, a total of 12 studies were rated as strong, 3 studies were rated as moderate and 3 were rated as weak. Taken as a whole, the results suggest that occupational exposure to different anesthetic agents may induce genome damage and that the micronucleus assay appears to be a reliable and suitable DNA damage biomarker for professionals chronically exposed to anesthetics.
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| http://dx.doi.org/10.1080/09603123.2024.2421834 | DOI Listing |
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