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Feasibility of reconstructingpatient 3D dose distributions from 2D EPID image data using convolutional neural networks.
Phys Med Biol
January 2025
School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, People's Republic of China.
. The primary purpose of this work is to demonstrate the feasibility of a deep convolutional neural network (dCNN) based algorithm that uses two-dimensional (2D) electronic portal imaging device (EPID) images and CT images as input to reconstruct 3D dose distributions inside the patient..
View Article and Find Full Text PDFExploring Metabolic Approaches for Epithelial Ovarian Cancer Therapy.
J Cell Physiol
December 2024
Fels Cancer Institute for Personalized Medicine and Department of Cancer and Cellular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Epithelial ovarian cancer (EOC) has the highest mortality rate among malignant tumors of the female reproductive system and the lowest survival rate. This poor prognosis is due to the aggressive nature of EOC, its late-stage diagnosis, and the tumor's ability to adapt to stressors through metabolic reprogramming. EOC cells sustain their rapid proliferation by altering the uptake, utilization, and regulation of carbohydrates, lipids, and amino acids.
View Article and Find Full Text PDFPain in Palliative Cancer Patients - Analysis of the German National Palliative Care Registry.
J Pain Symptom Manage
February 2025
Department of Psychosomatic Medicine and Psychotherapy (M.R., M.L.C., K.S., J.J., R.C.), University Hospital Münster, Münster, Germany; West German Cancer Center (M.R., K.S., R.C.), University Hospital Münster, Münster, Germany.
Context: Palliative care aims to improve the quality of life in patients with progressive diseases such as cancer. Effective cancer pain management is a major challenge of palliative treatment. Empirical data on the prevalence of cancer pain, the efficiency of pain treatment and influencing factors are scarce.
View Article and Find Full Text PDFA New Hope: Patient-Specific Bone-Anchored Subperiosteal Implants: Perspective of 3 US Institutions on This Resurrected Treatment Modality.
J Oral Maxillofac Surg
October 2024
Professor of Surgery, Director, Craniomaxillofacial Trauma Program, Division of Plastic, Maxillofacial & Oral Surgery, Duke University Medical Center, Durham, NC.
Impact of Surgeon-Radiation Oncology Dyads in Oral Cavity Cancer Outcomes.
Ann Surg Oncol
February 2025
Department of Otolaryngology - Head and Neck Surgery, University of Toronto, Toronto, ON, Canada.
Background: Multidisciplinary care is paramount in patient-specific decision making, especially as pertaining to oral cavity squamous cell cancer (OCSCC) treatment. Protracted surgery-postoperative-radiation (S-PORT) has a detrimental impact on OCSCC patients' outcomes. This study examined the impact of surgeon-radiation oncologist dyads on the treatment of OCSCC, focusing on S-PORT interval and disease specific outcomes.
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