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Exploring the therapeutic potential of polysaccharide from Portulaca oleracea L.: A review of phytochemistry and immunomodulatory effect. | LitMetric

AI Article Synopsis

  • Portulaca oleracea L. (commonly known as purslane) is recognized for its edible and medicinal benefits, historically used in traditional medicine for diuretic and other therapeutic properties.
  • The focus of current research on its polysaccharide component (POP) highlights its diverse biological activities, particularly in immune system modulation, prompting extensive studies on its extraction and characterization.
  • This review aims to clarify the pharmacological mechanisms and molecular pathways of POP while identifying gaps in current knowledge and proposing new avenues for research to enhance understanding of its health benefits.

Article Abstract

Portulaca oleracea L., a plant with both edible and medicinal properties, is traditionally valued for its diuretic, antipyretic, antiseptic, antispasmodic, and anthelmintic functions in folk medicine. P. oleracea polysaccharide (POP), a pivotal bioactive component, has various biological activities. Notably, their immunomodulatory capabilities have emerged as a significant area of research. The extraction, purification, monosaccharide composition, structure characterization, and biological activity of POP have been extensively investigated to identify the active components and to clarify their pharmacological actions and underlying molecular mechanisms. It aims to delineate the pharmacological mechanisms and molecular pathways associated with these polysaccharides, thereby underscoring their therapeutic promise and nutritional significance. Furthermore, the review critically examines the current research landscape of POP, identifying gaps and proposing innovative perspectives to enrich the scientific discourse surrounding these bioactive compounds.

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Source
http://dx.doi.org/10.1016/j.carres.2024.109298DOI Listing

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