AI Article Synopsis
- The study investigates the effects of an intensified nutrition management (iNM) protocol on patients undergoing esophagectomy for esophageal cancer, comparing it to conventional nutrition management (cNM).
- It included 126 patients, showing that the iNM group received more frequent nutritional counseling, leading to higher compliance rates and better outcomes in body weight and skeletal muscle index (SMI) after surgery.
- The results suggest that outpatient iNM effectively reduces body weight loss and SMI decline within 3 to 6 months post-surgery, improving overall nutritional status.
Article Abstract
Background: The progression of malnutrition and sarcopenia after esophagectomy for esophageal cancer negatively influences long-term prognosis. To improve nutritional status after esophagectomy, we introduced an intensified nutrition management (iNM) protocol, in which nutritional counselling by dietitians was provided more frequently. The aim of this study was to evaluate the efficacy of iNM compared with the conventional NM (cNM).
Methods: We included 126 patients who underwent esophagectomy before and after NM revision, and compared nutritional status and changes in body composition after esophagectomy between the cNM and iNM groups. Nutritional parameters were assessed, and we also calculated skeletal muscle index (SMI), skeletal muscle density (SMD), and visceral fat area (VFA) using computed tomography volumetry.
Results: There were no significant differences in baseline characteristics or surgical outcomes between the groups. Compared with the cNM group, nutritional counselling was provided more frequently (P < 0.001) in the iNM group, and compliance rate increased from 56.3 to 91.9% (P < 0.001). Body weight loss at 4 and 6 months and SMI reduction at 6 months were significantly improved in the iNM group compared with the cNM group (P < 0.001, P = 0.032, and P = 0.023, respectively). There were no significant differences in the changes in SMD, VFA, serum albumin level, and prealbumin level between the two groups.
Conclusions: Outpatient iNM significantly mitigated the reduction in body weight and SMI 3-6 months after esophagectomy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11532320 | PMC |
| http://dx.doi.org/10.1007/s00423-024-03526-2 | DOI Listing |
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