AI Article Synopsis
- Understanding the deep brain's architecture is difficult due to its complex structure, which controls movement and behavior, and lacks dedicated exploration tools.
- A new deep-brain MRI architecture atlas was created using advanced MRI-based mapping techniques, featuring a young male adult template and various MRI datasets.
- This open-source tool includes high-resolution images of 118 labeled deep brain structures, enhancing existing 3D atlases and clinical resources for better analysis.
Article Abstract
Understanding the architecture of the human deep brain is especially challenging because of the complex organization of the nuclei and fascicles that support most sensorimotor and behaviour controls. There are scant dedicated tools to explore and analyse this region. Here we took a transdisciplinary approach to build a new deep-brain MRI architecture atlas drawing on advanced clinical experience of MRI-based deep brain mapping. This new tool comprises a young-male-adult MRI template spatially normalized to the ICBM152, containing T1, inversion-recovery, and diffusion MRI datasets (in vivo acquisition), and an MRI atlas of 118 labelled deep brain structures. It is open-source and gives users high resolution image datasets to describe nuclear-based and axonal architecture, combining pioneering and recent knowledge. It is a useful addition to current 3D atlases and clinical tools.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530659 | PMC |
| http://dx.doi.org/10.1038/s41597-024-04053-x | DOI Listing |
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