AI Article Synopsis
- The maternal-child clinical trial networks, funded by NIH since the 1990s, have evolved to include both US domestic and international sites under a unified agenda.
- Their focus is on therapeutics for HIV prevention and treatment, the search for an HIV cure, addressing tuberculosis, and complications of HIV affecting the brain.
- Success has stemmed from strong community partnerships, collaboration with industry, and an understanding that treatments must be tailored to diverse populations.
Article Abstract
The clinical trial networks that included a maternal-child focus have evolved since first funded by NIH in the 1990s. Since then, US domestic and international sites were combined into one network, with a focused agenda on therapeutics (for both prevention and treatment), human immunodeficiency virus (HIV) cure, tuberculosis, and complications of HIV, largely specific to the brain. Key to the success of the network has been a strong partnership with the community, collaborations with industry and other strategic partners, and recognition that one size does not fit all when it comes to antiretrovirals, diagnosing and treating TB, and other treatments for our populations.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531646 | PMC |
| http://dx.doi.org/10.1016/j.clp.2024.08.009 | DOI Listing |
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