TAM-ing the beast with IL-34 blockade.

Sci Immunol

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Published: November 2024

mutation triggers IL-34 secretion by cancer stem cells, reprogramming macrophages to suppress T cells and promote tumor immune escape.

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Source
http://dx.doi.org/10.1126/sciimmunol.adu0981DOI Listing

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