AI Article Synopsis
- * The review discusses how probiotics can influence gut microbiota and metabolism, potentially reducing cognitive decline and inflammation through mechanisms like the gut-brain axis.
- * Probiotics may serve as a targeted approach to restore gut health, potentially slowing down aging, managing age-related diseases, and improving overall quality of life.
Article Abstract
Context: The age-induced disruption of gut flora, termed gut dysbiosis, is intimately tied to compromised immune function, augmented oxidative stress and a spectrum of age-linked disorders.
Objective: This review examines the fundamental mechanisms employed by probiotic strains to modulate gut microbiota composition and metabolic profiles, mitigate cognitive decline the gut-brain axis (GBA), modulate gene transcription and alleviate inflammatory responses and oxidative stress.
Conclusion: We elucidate the capacity of probiotics as a precision intervention to restore gut microbiome homeostasis and alleviate age-related conditions, thereby offering a theoretical framework for probiotics to decelerate ageing, manage age-related diseases, and elevate quality of life.
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| http://dx.doi.org/10.1080/1354750X.2024.2424388 | DOI Listing |
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