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| http://dx.doi.org/10.1016/j.waojou.2024.100978 | DOI Listing |
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Transcriptomic Profiles in Nasal Epithelium and Asthma Endotypes in Youth.
JAMA
January 2025
Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: T helper 2 (T2) cells and T helper 17 (T17) cells are CD4+ T cell subtypes involved in asthma. Characterizing asthma endotypes based on these cell types in diverse groups is important for developing effective therapies for youths with asthma.
Objective: To identify asthma endotypes in school-aged youths aged 6 to 20 years by examining the distribution and characteristics of transcriptomic profiles in nasal epithelium.
Panthenol Allergic Contact Dermatitis: Sources of Exposure, Reported Cases, and a Call for More Frequent Testing.
Dermatitis
December 2024
From the Department of Dermatology, Park Nicollet Contact Dermatitis Clinic, Minneapolis, MN, USA.
Panthenol, a vitamin B5 derivative, is a key precursor in the synthesis of fatty acids that maintain epithelial function. Its ability to aid in moisturization, skin barrier restoration, and wound healing has led to its frequent incorporation into personal care products and pharmaceuticals-many of which are marketed to be hypoallergenic. While contact allergy to panthenol is rather uncommon, rates of positive reactions are on the rise, increasing from 0.
View Article and Find Full Text PDFProgress in genetic engineering and genome editing of peanuts: revealing the future of crop improvement.
Physiol Mol Biol Plants
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Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST), Department of Plant and Soil Sciences, Texas Tech University, Lubbock, 79403 USA.
Peanut ( L.), also known as groundnut, is cultivated globally and is a widely consumed oilseed crop. Its nutritional composition and abundance in lipids, proteins, vitamins, and essential mineral elements position it as a nutritious food in various forms across the globe, ranging from nuts and confections to peanut butter.
View Article and Find Full Text PDFThe Preventive Effect of Zinc Sulfate against Olanzapine-Induced Testicular Toxicity in Male Rats.
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Institute of Specific Prophylaxis and Tropical Medicine [ISPTM], Center for Pathophysiology, Infectiology and Immunology [CePII], Ocular Immunology & Infectiology, Medical University of Vienna, Vienna, Austria.
Male infertility is a complex and multifactorial clinical condition affecting a large population attributed to several factors, including perturbation in oxidative stress and the level of essential trace elements. Oxidative stress exerts multiple issues related to reproductive health, including male infertility, decreased sperm motility, sperm DNA damage, and an increased susceptibility to genetic disorders. Besides chemical toxins and food allergens in junk food items, many drugs can also lead to male infertility.
View Article and Find Full Text PDFSynergistic effects of vitamin C mitigates sodium fluoride-induced dental fluorosis and allergic immune responses in mice.
Food Chem Toxicol
November 2024
Department of Biotechnology & Bioinformatics, School of Life Sciences, JSS Academy of Higher Education & Research, Mysore, Karnataka, 570015, India. Electronic address:
Fluoride consumption through food and drinking water above permissible levels poses serious health risks. Managing fluoride intake from community water sources is a considerable challenge. This study aimed to understand the synergistic effect of vitamin C supplementation in a mouse model exposed to sodium fluoride (NaF) and ovalbumin (OVA) allergen.
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