AI Article Synopsis

  • - Colchicine is increasingly being used to treat cardiovascular diseases but can be very dangerous in overdose situations.
  • - Overdosing on colchicine causes direct damage to heart cells, which can result in severe heart failure.
  • - The case study discusses a patient who experienced a colchicine overdose and required advanced life support, showcasing the difficulties in managing such emergencies.

Article Abstract

Colchicine has an expanding role in cardiovascular disease treatment. Colchicine overdose is a toxicologic emergency. Direct cellular toxicity interferes with myocardial contractility, leading to cardiovascular collapse. We present a case of a patient with a colchicine overdose supported with venoarterial extracorporeal membrane oxygenation, highlighting the challenges and limitations.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522767PMC
http://dx.doi.org/10.1016/j.jaccas.2024.102580DOI Listing

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