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Radiation Proctitis: A Review of Pathophysiology and Treatment Strategies. | LitMetric

AI Article Synopsis

  • Radiotherapy (RT) is a key cancer treatment that uses high-energy rays to stop tumor growth, especially for pelvic cancers.
  • Radiation proctitis is a common side effect of RT, presenting in various forms and influenced by individual patient factors; while often self-limiting, it can become chronic and diminish quality of life.
  • Although several treatment options are available for radiation proctitis, there is no agreed-upon protocol, and the text discusses its causes, influencing factors, and potential treatment strategies.

Article Abstract

Radiotherapy (RT) has become an integral part of cancer treatment worldwide; it aims to arrest the uncontrolled growth of tumor cells by using high-energy rays. Radiation proctitis is a known clinical manifestation after the RT regime for pelvic malignancies. Radiation proctitis can have a variable presentation, and there are a lot of patient-related factors that can affect the eventual outcome. In most instances, it is self-limiting; however, it can become chronic in some cases and can affect the quality of life. Many treatment options are recommended, but there has been no consensus on the treatment protocols for managing this known clinical condition. We have tried to briefly describe its pathogenesis, important factors affecting the outcome, and available treatment strategies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525059PMC
http://dx.doi.org/10.7759/cureus.70581DOI Listing

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