A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Navigating cold agglutinin-induced hemolytic anemia in developing countries: A case report and literature review. | LitMetric

AI Article Synopsis

  • Cold agglutinin-induced hemolytic anemia poses diagnostic challenges, especially in resource-limited settings like Pakistan, highlighted by a case of a 92-year-old male with severe anemia and altered consciousness.
  • Diagnosis was confirmed through positive Direct Coombs test and elevated cold agglutinin titers, demonstrating the importance of specific lab findings in identifying the condition.
  • Multidisciplinary management, including blood transfusions and immunosuppressive therapy, resolved the patient's symptoms, underscoring the need for enhanced clinician awareness and timely interventions for better patient outcomes.

Article Abstract

Cold agglutinin-induced hemolytic anemia presents diagnostic and management challenges, particularly in resource-limited settings like Pakistan. A 92-year-old male presented with altered consciousness, fever, weakness, and severe asthenia. Laboratory findings revealed severe anemia, elevated mean corpuscular volume, and deranged renal function tests. The diagnosis was confirmed via a positive Direct Coombs test and elevated cold agglutinin titers. Multidisciplinary management led to symptom resolution, including blood transfusions and immunosuppressive therapy. This case report and literature review emphasize the complexities of diagnosing and managing cold agglutinin-induced hemolytic anemia in Pakistan. By enhancing awareness and understanding of this condition, clinicians can optimize patient outcomes through timely intervention and multidisciplinary care.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526302PMC
http://dx.doi.org/10.1177/2050313X241288352DOI Listing

Publication Analysis

Top Keywords

cold agglutinin-induced
12
agglutinin-induced hemolytic
12
hemolytic anemia
12
case report
8
report literature
8
literature review
8
navigating cold
4
anemia
4
anemia developing
4
developing countries
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!