AI Article Synopsis
Article Abstract
The pattern recognition receptor (PRR), which drives innate immunity, shields the host against invasive pathogens. Fish and other aquatic species with poorly developed adaptive immunity mostly rely on their innate immunity, regulated by PRRs such as inherited-encoded toll-like receptors (TLRs). The discovery of 21 unique TLR variations in various aquatic animals over the past several years has sparked interest in using TLRs to improve aquatic animal's immune response and disease resistance. This comprehensive review provides an overview of the latest investigations on the various characteristics of TLRs in aquatic animals. It emphasizes their categorization, insights into 3D architecture, ligand recognition, signaling pathways, TLRs mediated immune responses under biotic and abiotic stressors, and expression variations during several developmental stages. It also highlights the differences among aquatic animals' TLRs and their mammal counterparts, which signifies the unique roles that TLRs play in aquatic animal's immune systems. This article summarizes current aquaculture research to enhance our understanding of fish immune systems for effective aquaculture -related disease management.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524855 | PMC |
| http://dx.doi.org/10.3389/fimmu.2024.1378111 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Toxicity effects of microplastics individually and in combination with Aeromonas hydrophila on freshwater crayfish (Astacus leptodactylous).
Environ Sci Pollut Res Int
December 2024
Division of Aquatic Animal Health & Diseases, Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Opportunistic pathogens, such as Aeromonas hydrophila, can cause damage to freshwater crayfish (Astacus leptodactylous) in some situations. In addition to direct damage to the body, microplastics (MPs) can also be responsible for transmitting pathogens to the animal. Accordingly, this research was prepared to investigate the effects of MP on the damage caused by A.
View Article and Find Full Text PDFChlorpyrifos Influences Tadpole Development by Disrupting Thyroid Hormone Signaling Pathways.
Environ Sci Technol
December 2024
Institute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, P. R. China.
Chlorpyrifos (CPF) is a widely used organophosphate insecticide with serious toxicological effects on aquatic animals. Although extensively studied for neurotoxicity and endocrine disruption, its stage-specific effects on amphibian metamorphosis and receptor-level interactions remain unclear. This study investigated the effects of CPF on metamorphosis at environmentally relevant concentrations (1.
View Article and Find Full Text PDFDevelopment and Characterisation of an Immortal Cell Line From Largemouth Bass (Micropterus salmoides) for Viral Studies.
J Fish Dis
December 2024
Key Laboratory of Fishery Drug Development, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Aquatic Animal Immunology and Sustainable Aquaculture, Pearl River Fishery Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, China.
Largemouth bass (Micropterus salmoides), a freshwater fish species, is cultivated widely across China. The industry has been greatly affected by various viral diseases. We generated a new immortal cell line from the fin of M.
View Article and Find Full Text PDFModeling the effects of water temperature on the population dynamics of and infection by : a two-year survey in Andean Patagonia, Argentina.
PeerJ
December 2024
Grupo de Salud Animal, Instituto Nacional de Tecnología Agropecuaria (INTA), San Carlos de Bariloche, Río Negro, Argentina.
Background: The trematode parasite (liver fluke) can infect livestock, wild mammals, and humans, generating serious economic losses worldwide. Aquatic or amphibious snails of the Lymnaeidae family are the intermediate host of this parasite. Both snail population dynamics and parasite development are closely associated with temperature, although most field studies have recorded air temperature rather than water temperature.
View Article and Find Full Text PDFNovel Amazonian Ceratomyxa species (Cnidaria: Myxozoa) with amoeboid plasmodial motility.
Microb Pathog
December 2024
Universidade Federal de São Paulo, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Diadema, São Paulo, Brasil, CEP 09972-270; Universidade Estadual de Campinas, Instituto de Biologia, Campinas, Brasil, CEP 13083-862.
Myxosporeans are a diverse group of cnidarian endoparasites of aquatic animals, with more than 2,600 described species. The genus Ceratomyxa includes some 270 species that are mostly coelozoic and infect the gall bladders of mainly marine fish. During our survey in Tapajós River in the Brazilian Amazon, two Ceratomyxa species were discovered in the gallbladders of the anostomid fishes Schyzodon fasciatus and Schyzodon vittatus.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!