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Exosomes-Derived MiR-302b Suppresses Lung Cancer Cell Proliferation and Migration via TGFβRII Inhibition.
Cell Physiol Biochem
February 2017
Background/aims: Several studies have reported that tumor-derived exosomes contain kinds of miRNAs, including oncogenic miRNAs and tumor suppressor miRNAs. It has been reported that miR-302b could inhibit cancer progression by targeting oncogenes post-transcriptionally. Whether miR-302b is involved in the regulation of tumor-derived exosomes on lung cancer cells proliferation has not yet been demonstrated.
View Article and Find Full Text PDFRETRACTED: miRNA-302b suppresses human hepatocellular carcinoma by targeting AKT2.
Mol Cancer Res
February 2014
Department of Genetics and Molecular Biology, Xi'an Jiaotong, University School of Medicine, 76 Yan Ta West Road, Xi'an, Shaanxi 710061, China.
Unlabelled: miRNAs (miR) play a critical role in human cancers, including hepatocellular carcinoma. Although miR-302b has been suggested to function as a tumor repressor in other cancers, its role in hepatocellular carcinoma is unknown. This study investigated the expression and functional role of miR-302b in human hepatocellular carcinoma.
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