Metabolic Brain PET Connectivity.

PET Clin

Aix Marseille Univ, Marseille, France; CERIMED, CNRS, Centrale Marseille, Institut Fresnel, Marseille, France; Nuclear Medicine Department, AP-HM, Timone Hospital, Marseille, France.

Published: January 2025

This review examines the role of metabolic connectivity based on fluorodeoxyglucose-PET in understanding brain network organization across neurologic disorders, with a focus on neurodegenerative diseases. The article explores key methodologies for metabolic connectivity study and highlights altered connectivity patterns in Alzheimer's, Parkinson's, frontotemporal dementia, and other conditions. It also discusses emerging applications, including single-subject analyses and brain-organ interactions.

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http://dx.doi.org/10.1016/j.cpet.2024.09.014DOI Listing

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