Rationale And Objectives: This study aimed to address the challenge of predicting treatment outcomes for patients with uterine fibroids undergoing high-intensity focused ultrasound (HIFU) ablation. We developed medical-assisted diagnostic models to accurately predict the ablation rates and volume reduction rates, thus assessing both short-term and long-term treatment effects of fibroids.
Materials And Methods: For the ablation rate prediction, our study included 348 fibroids, categorized into 181 fully ablated and 167 inadequately ablated fibroids. Using multimodal MRI sequences and clinical characteristics, coupled with data preprocessing steps such as feature extraction, testing, and screening, we constructed an ensemble model for predicting preoperative ablation rates. In the volume reduction rate study, we analyzed 253 fibroids, divided into 142 high-volume responders and 111 low-volume responders. Based on clinical characteristics and T2-weighted image (T2WI) sequences, along with lesion delineation, feature normalization, and other preprocessing steps, we developed an inter-slice information fusion model for predicting preoperative volume reduction rates.
Results: The ensemble model demonstrated an accuracy of 0.800 and an area under the curve (AUC) of 0.830 on the test set, while the inter-slice information fusion model achieved an accuracy of 0.808 and an AUC of 0.891. Both models showed superior predictive performance compared to existing models.
Conclusion: The ensemble and inter-slice information fusion models developed in this study exhibit robust predictive capabilities, offering valuable support for clinicians in selecting patients for HIFU treatment. These models hold potential for enhancing patient outcomes through tailored treatment planning.
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http://dx.doi.org/10.1016/j.acra.2024.09.040 | DOI Listing |
Water Res
December 2024
School of Chemistry and Environment, Guangdong Ocean University, Zhanjiang, 524088, China; Analyzing and Testing Center, Guangdong Ocean University, Zhanjiang, 524088, China; Analytical and Testing Center for Ocean in Western of Guangdong Province, Guangdong Provincial Observation and Research Station for Tropical Ocean Environment in Western Coastal Water, Guangdong Ocean University, Zhanjiang, 524088, China. Electronic address:
Corals are representative of typical symbiotic organisms. The coral-algal (Symbiodinium spp.) symbiosis drives the productivity of entire coral reefs.
View Article and Find Full Text PDFEur J Appl Physiol
December 2024
Sports Performance Research Institute New Zealand, Auckland University of Technology, Auckland, New Zealand.
Purpose: To determine the effect of carbohydrate ingestion during prolonged exercise on durability of the moderate-to-heavy-intensity transition and severe-intensity performance.
Methods: Twelve trained cyclists and triathletes (10 males, 2 females; peak, 59 ± 5 mL kg min; training volume, 14 ± 5 h week) performed an incremental test and 5-min time trial (TT) without prior exercise (PRE), and after 150 min of moderate-intensity cycling, with (POST) and without (POST) carbohydrate ingestion.
Results: Power output at the first ventilatory threshold (VT) was lower in POST (225 ± 36 W, ∆ -3 ± 2%, P = 0.
BMC Med Educ
December 2024
Department of Anesthesiology and Pain Medicine, the Affiliated Hospital of Jiaxing University, No.1882, South of the Second Ring Road, Jiaxing City, Zhejiang Province, 314000, China.
Background: Radial artery cannulation can be challenging, particularly for inexperienced providers. This study aimed to compare the success rates of resident physicians performing radial artery cannulation with mild sedation and analgesia versus without.
Materials And Methods: This study was a prospective, single-center, double-blind randomized controlled trial.
BMC Pulm Med
December 2024
Department of Endocrinology and Metabolism, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518033, China.
J Voice
December 2024
Indiana University School of Medicine (IUSM), Indianapolis, Indiana; IUSM Department of Otolaryngology-Head and Neck Surgery, Indianapolis, Indiana; Purdue University Department of Speech, Language, and Hearing Sciences, West Lafayette, Indiana. Electronic address:
Objectives/hypothesis: Given the complex pathology underlying unilateral vocal fold paralysis (UVFP), there has been limited systematic exploration of curative treatments in humans. Central to the investigation of experimental therapies includes establishing a reliable and analogous large animal model. The study goal was to create a standardized porcine model of UVFP by establishing characteristic pathophysiology and functional outcomes.
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