Objectives: Skeletal class III malocclusion presents either with maxillary retrognathism, mandibular excess, or a combination. Dentoalveolar compensations occur with maxillary incisor proclination and mandibular incisor retroclination. The aim of this study is to quantify the amount of incisal compensation in class III skeletal malocclusion and correlate it to the severity of the skeletal base.
Materials And Methods: Eleven angular and 7 linear cephalometric measurements were digitized from 57 patients. Axial inclination of the upper and lower incisors was evaluated for compensation. Pearson's correlation coefficient was used to determine the dentoalveolar parameter among those measuring upper and lower incisor position and inclination that correlated most highly with the severity of class III. Linear regression analysis was used to identify the quantum of the incisal compensation.
Results: Upper incisors were proclined and placed anteriorly. However, correlation analysis suggested a less responsive incisor with progressive change in skeletal base. Lower incisors began to compensate only as the severity of class III increased. For every degree of reduction of ANB angle from normal, the incisor mandibular plane angle (IMPA) and L1-GoMe decreased by 0.79° and the L1-GoGn decreased by 0.81°.
Conclusion: The upper incisors contributed more to compensation compared to the lower incisors in a class III skeletal base. As class III severity increased, the upper incisor compensation decreased while that of lower incisors increased. For every degree of reduction in ANB angle, the IMPA and L1-GoMe decreased by 0.79° and the L1-GoGn decreased by 0.81°.
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http://dx.doi.org/10.5125/jkaoms.2024.50.5.265 | DOI Listing |
Am J Orthod Dentofacial Orthop
December 2024
Department of Orthodontics, Teerthanker Mahavir Dental College and Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India.
Introduction: The primary objective of this study was to assess the 3-dimensional position of the mandibular canal (MC) in different craniofacial patterns to know about the safe placement of temporary skeletal anchorage devices using cone-beam computed tomography (CBCT). The secondary objectives were to assess sex differences and correlate the MC position with various factors.
Methods: This prospective, observational study was conducted on 90 patients, divided into 3 groups based on the sagittal pattern: skeletal Class I, Class II, and Class III.
Neurol Int
December 2024
Department of Immunology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.
: Several significant associations between certain Human Leukocyte Antigen (HLA) alleles and myasthenia gravis (MG) subtypes were established in populations from Western Europe and North America and, to a lesser extent, from China and Japan. However, such data are scarcely available for Eastern Europe. This study aimed to analyze the associations of HLA Class I and II alleles with MG and its serological subtypes (with anti-acetylcholine receptor autoantibodies, RAch+MG, and double-seronegative, dSNMG) in myasthenic patients of Romanian descent.
View Article and Find Full Text PDFJ Pers Med
December 2024
Cardiology Unit, Ospedale del Cuore, Fondazione Toscana "G. Monasterio", 54100 Massa, Italy.
Elderly patients with severe aortic stenosis (AS) need individualized decision-making in their management in order to benefit in terms of survival and improvement of quality of life. Frailty, a common condition in elderly patients, needs to be considered when weighing treatment options. We aimed to evaluate outcomes including survival and functional parameters according to disability criteria at six years of follow-up in an older population treated for severe AS using a frailty-based management.
View Article and Find Full Text PDFJ Antimicrob Chemother
December 2024
Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Background: Major adverse cardiovascular events (MACEs) may contribute to the high morbidity in people with four-class drug-resistant HIV (4DR-PWH).
Objectives: To explore the probability of MACEs in 4DR-PWH compared with non-4DR controls.
Methods: This was a retrospective, propensity score-matched cohort study on 4DR-PWH (cases) and non-4DR-PWH (controls), on ART, without previous MACEs.
Adv Mater
December 2024
School of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong (CUHK-Shenzhen), Shenzhen, Guangdong, 518172, P. R. China.
The existence of residual small-size tumors after surgery is a major factor contributing to the high recurrence rate of glioblastoma (GBM). Conventional adjuvant therapeutics involving both chemotherapy and radiotherapy usually exhibit unsatisfactory efficacy and severe side effects. Recently, two-photon photodynamic therapy (TP-PDT), especially excited by the second near-infrared (NIR-II) light, offers an unprecedented opportunity to address this challenge, attributed to its combinational merits of PDT and TP excitation.
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