Efficacy of dextrose prolotherapy on temporomandibular disorder: a retrospective study.

J Korean Assoc Oral Maxillofac Surg

Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea.

Published: October 2024

Objectives: Dextrose prolotherapy is one of the most promising minimally invasive interventions for temporomandibular disorder (TMD), particularly in refractory cases where other conservative treatments have failed. The purpose of this study was to demonstrate the efficacy of a new treatment, temporomandibular joint (TMJ) prolotherapy, in patients with TMD to alleviate symptoms.

Materials And Methods: A retrospective analysis was conducted on TMD patients with chronic pain who did not respond to conventional treatments. TMJ prolotherapy was performed using hypertonic dextrose in the TMJ area, targeting the retrodiscal attachment tissue, anterior disc attachment tissue, lateral capsule, origin of the masseter muscle, and the stylomandibular ligament. Pain or discomfort intensity in the TMJ was evaluated using a numerical rating scale (NRS). Maximum mouth opening and subjective satisfaction were also analyzed.

Results: Nineteen patients (6 males, 13 females, average age 43 years) participated in this study. All patients experienced pain improvement with a maximum of three prolotherapy sessions. The initial mean NRS was 5.7, which ultimately decreased to a final mean TMJ discomfort score of 1.7 postintervention. The patients' maximum mouth opening increased from an initial 34.5 mm to 38.8 mm, and they reported positive satisfaction with the prolotherapy treatment. The clinical outcomes were positive regardless of main origin of TMD symptoms.

Conclusion: Hypertonic TMJ prolotherapy is an effective minimally invasive intervention for TMJ disorders with chronic pain.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11535124PMC
http://dx.doi.org/10.5125/jkaoms.2024.50.5.259DOI Listing

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Efficacy of dextrose prolotherapy on temporomandibular disorder: a retrospective study.

J Korean Assoc Oral Maxillofac Surg

October 2024

Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea.

Objectives: Dextrose prolotherapy is one of the most promising minimally invasive interventions for temporomandibular disorder (TMD), particularly in refractory cases where other conservative treatments have failed. The purpose of this study was to demonstrate the efficacy of a new treatment, temporomandibular joint (TMJ) prolotherapy, in patients with TMD to alleviate symptoms.

Materials And Methods: A retrospective analysis was conducted on TMD patients with chronic pain who did not respond to conventional treatments.

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Objective: We reviewed the efficacy of dextrose prolotherapy versus placebo and other active interventions, like autologous blood injection (ABI) and botulinum toxin (BTX), in improving the outcomes of temporomandibular joint (TMJ) hypermobility.

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Article Synopsis
  • The study investigated the effectiveness of 10% dextrose prolotherapy for treating temporomandibular joint disorders (TMDs) in 30 patients who had symptoms for over six months and didn't respond to other treatments.
  • The treatment involved four injection sessions over three months, with assessments made on pain, joint locking, and mouth opening at each visit.
  • Results showed significant improvement in TMD symptoms, suggesting that dextrose prolotherapy could be a viable alternative to long-term medications or surgery.
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Introduction: Prolotherapy is a minimally invasive technique that aims to functionally restore or repair the soft and hard tissues of the TMJ by injecting a stimulant. The present study was conducted to compare the effectiveness of dextrose and autologous blood injection (ABI) as prolotherapy agents in the treatment of patients with chronic recurrent TMJ dislocation (CRTD).

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