AI Article Synopsis
- Inhalation of particulate matter (PM) can lead to increased reactive oxygen species (ROS) in the lungs, causing inflammation and potentially leading to respiratory and cardiovascular diseases.
- This study evaluated the oxidative potential (OP) of fresh and aged PM from different urban and rural sources, finding that biomass burning produces the highest OP, followed by industrial, vehicular, and cooking emissions.
- Aged PM exhibited reduced OP due to changes in its chemical structure, with various components responding differently to aging, emphasizing the need for targeted health protection policies based on PM sources.
Article Abstract
Inhalation of atmospheric PM can induce the generation of excessive reactive oxygen species (ROS) in human alveoli, triggering local and systemic inflammation, which can directly or indirectly result in respiratory and cardiovascular diseases. In this study, we assessed the oxidative potential (OP) of fresh and O-aged PM particles from various urban and rural emission sources using the dithiothreitol (DTT) method. Our results revealed variations in the OP of fresh PM among different emission sources, with biomass burning sources exhibiting the highest OP, followed by industrial areas, vehicular emissions, cooking emissions, and suburban areas, respectively. Water-soluble organics and transition metals might potentially exert significant influence on particle OP. O aging notably decreased the OP of PM particles, possibly due to the oxidation of highly DTT-active components into low redox-active small molecules. Moreover, the evolution of OP in different PM components, including methanol-soluble and insoluble fractions, exhibited distinct responses to O aging for source-oriented PM. Additionally, differences in chemical composition between fresh and aged PM were further elucidated through measurements of component-dependent hygroscopic behaviors and phase transitions. This study systematically delineates variances in the toxic potential of fresh and O-aged PM from various anthropogenic sources. The findings highlight the intrinsic compositional dependence of particle OP and provide essential insights for assessing the health effects of source-oriented PM, as well as for formulating human health protection policies.
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| http://dx.doi.org/10.1016/j.jes.2024.04.023 | DOI Listing |
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