Introduction: The relationship between vertical facial patterns and the morphology of the alveolar bone and teeth is crucial for successful orthodontic treatment planning. This study aimed to evaluate the relationship between vertical facial patterns, bone thickness, and root-crown dimensions in the maxillary anterior teeth.
Methods: This retrospective study screened 300 cone-beam computed tomography (CBCT) scans of orthodontic patients between December 2022 and November 2023, with 115 meeting the inclusion criteria. Buccal and lingual alveolar bone thickness, along with crown and root lengths of maxillary anterior teeth, were measured and compared across short, normal, and long facial types, classified according to the Frankfort-Mandibular Plane Angle. One-way ANOVA, independent-samples Kruskal-Wallis, and post-hoc tests were used for statistical analysis.
Results: Significant differences in alveolar bone thickness were observed across facial types, with short facial types showing consistently greater thickness in the apical and mid-palatal regions compared to normal and long facial types (p < 0.05). No significant differences in crown or root lengths were found among the facial types.
Conclusion: Facial type significantly influences alveolar bone thickness, particularly in short facial types, which demonstrate greater bone support. These findings underscore the importance of considering facial type in orthodontic treatment planning to minimize complications.
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http://dx.doi.org/10.1016/j.jormas.2024.102128 | DOI Listing |
Adv Healthc Mater
January 2025
School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW, 2006, Australia.
Orthopedic, maxillofacial, and complex dentoalveolar bone grafting procedures that require donor-site bone harvesting can be associated with post-surgical complications. There has been widespread adoption of exogenously sourced particulate bone graft materials (BGM) for bone regenerative procedures; however, the particulate nature of these materials may lead to compromised healing outcomes, mainly attributed to structural collapse of the BGM, prolonged tissue healing. In this study, a fully synthetic thermoresponsive hydrogel-based universal carrier matrix (TX) that forms flowable and shapable putties with different BGMs while spatially preserving the particles in a 3D scaffold at the implantation site is introduced.
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
Department of Periodontology, School and Hospital of Stomotology, Tianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, Tianjin Medical University, Tianjin, China.
The combination of hydrophilic arginine residues and hydrophobic tryptophan residues is considered to be the first choice for designing short-chain antimicrobial peptides (AMPs) due to their potent antibacterial activity. Based on this, we designed an arginine- and tryptophan-rich short peptide, VR-12. Peri-implantitis is a significant microbial inflammatory disorder characterized by the inflammation of the soft tissues surrounding an implant, which ultimately leads to the progressive resorption of the alveolar bone.
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
Faculty of Dentistry, National University of Singapore, Singapore, Singapore.
Advances in tissue engineering and microfluidic technologies have enabled the development of sophisticated models known as organ-on-a-chip (OoC) or microphysiological systems. These systems enable to potential to simulate the dynamic interactions between host tissues and their microenvironment including microbes, biomaterials, mechanical forces, pharmaceutical, and consumer-care products. These fluidic technologies are increasingly being utilized to investigate host-microbe and host-material interactions in oral health and disease.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Qingdao Municipal Hospital, Shandong, 266071, China.
Background: Lip behaviors can lead to maxillofacial developmental disorders such as anterior open bite, posterior crossbite, increased overjet, and a higher risk of developing a Class II malocclusion. However, lip-sucking, a behavior often underreported and overlooked, may adversely affect the periodontal health of permanent teeth in adolescents under extreme conditions if not promptly identified and managed.
Case Presentation: We report a unique case of an 11-year-old boy with a severe periodontal-endodontic lesion on tooth 32, caused by prolonged, high-frequency, and high-intensity lip sucking.
J Clin Periodontol
January 2025
Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, China.
Aim: To investigate the involvement of low-density lipoprotein receptor-related protein 5 (LRP5) in inflammation and alveolar bone loss in periodontitis.
Materials And Methods: Gingival tissues were obtained from 10 periodontitis patients and 10 healthy individuals. Wild-type (WT) and osteoblast-specific Lrp5 conditional knock-out C57BL/6 (LRP5fl/fl;Oc-Cre) mice were used to establish a ligature-induced mouse model of periodontitis.
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