Background: Acute post-viral cough (APVC) is a disturbing complaint that may also affect the quality of life. As a result, APVC requires an adequate managing with antitussive medications. In this regard, levodropropizine is an effective and safe peripheral antitussive drug.
Methods: The present retrospective observational study collected data from children with APVC and treated with levodropropizine for up to seven days. Cough intensity and frequency, impact on children's and parents' sleep, school and games, treatment days, satisfaction, and adverse events were considered.
Results: Data from 92 children (mean age 5.5 years) were analyzed globally. Levodropropizine reduced cough intensity and frequency in most children and improved school and game activities and sleep quality in children and their parents. The treatment was safe. Most parents were highly satisfied with the results.
Conclusions: This experience showed that levodropropizine was an effective and safe remedy for children with acute post-viral cough.
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http://dx.doi.org/10.23736/S2724-5276.24.07691-2 | DOI Listing |
Infect Med (Beijing)
December 2024
Department of Cardiology, Cleveland Clinic Foundation, Ohio 44195, USA.
This review investigates the therapeutic potential of vagal nerve stimulation (VNS) in managing long COVID, a condition marked by persistent symptoms following acute SARS-CoV-2 infection. Long COVID manifests as ongoing fatigue, cognitive impairment, and autonomic dysfunction, hypothesized to arise from sustained inflammatory and neurological dysregulation. The vagus nerve, central to modulating systemic inflammation and autonomic homeostasis, represents a promising therapeutic target for symptom alleviation through VNS.
View Article and Find Full Text PDFNeurol Neurochir Pol
December 2024
Department of Neurology, Wroclaw Medical University, Wroclaw, Poland.
Aim Of Study: This study aimed to compare headache and facial pain prevalence and headache phenotype among people with common upper respiratory tract infections (URTIs).
Clinical Rationale For Study: Headache is a common symptom in viral URTI, but its phenotyping has so far been limited to coronavirus disease 2019 (COVID-19) and influenza. Additionally, the prevalence of facial pain in URTIs has only rarely been discussed in scientific publications.
Infect Med (Beijing)
December 2024
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8TA, UK.
Causal associations between viral infections and acute myocardial injury are not fully understood, with mechanisms potentially involving direct cardiovascular involvement or systemic inflammation. This review explores plausible mechanisms of vascular fibrosis in patients with post-COVID-19 syndrome, focusing on extracellular matrix remodelling. Despite global attention, significant mechanistic or translational breakthroughs in the management of post-viral syndromes remain limited.
View Article and Find Full Text PDFEpilepsy Behav
January 2025
Neuropediatric Clinic and Clinic for Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schoen-Klinik Vogtareuth, Vogtareuth, Germany.
Sci Rep
November 2024
Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School (MHH) OE 6810, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.
Viral infections can be acute or chronic, with the immune system pivotal in immunopathogenesis. The potential reversibility of inflammation post-viral elimination is of current interest. This study compares the dynamics of soluble inflammatory mediators (SIM) during and after respiratory infections with SARS-CoV-2 and blood-borne acute and chronic hepatitis C virus (HCV) infections.
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