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| http://dx.doi.org/10.1016/j.jaccao.2024.07.009 | DOI Listing |
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The Relationship Between Blood Pressure and Heart Rate Response During Exercise Testing with Microcirculation Indices.
High Blood Press Cardiovasc Prev
December 2024
First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Introduction: Hypertension is associated with changes in microcirculation, while increased blood pressure (BP) during exercise stress testing has been correlated with adverse outcomes.
Aim: To evaluate the relationship of microcirculation with exercise BP response in hypertensive individuals.
Methods: 105 hypertensive individuals underwent exercise stress testing and nail-fold videocapillaroscopy assessment, in order to evaluate the relationship of BP response to exercise with capillary density.
A Minimally-Invasive Swine Model of Chronic Kidney Disease-Associated Heart Failure.
Am J Physiol Heart Circ Physiol
December 2024
Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
Background: Chronic kidney disease (CKD) is on the rise, and over 50% of patients die from cardiac causes. Patients develop heart failure due to unelucidated reno-cardiac interactions, termed type 4 cardiorenal syndrome (CRS4). The aim of this study is to establish and characterize a reliable model of CRS4 in swine with marked cardiac diastolic dysfunction.
View Article and Find Full Text PDFNegative pressure breathing: the response of human respiration and circulation to different levels of rarefaction during inspiration.
Front Physiol
November 2024
Department of Cardiovascular and Respiratory Physiology in Extreme Environments, Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Russia.
Article Synopsis
- - Negative pressure breathing (NPBin) is a technique that lowers pressure in the respiratory tract during inhalation, aiming to boost blood flow to the heart and counteract fluid shifts in space.
- - This study analyzed the effects of NPBin for 25 minutes at pressure reductions of -10 to -25 cmHO, using various non-invasive measurement techniques to assess changes in circulation and respiration in healthy volunteers.
- - Results showed that NPBin increased tidal volume and decreased respiratory rate without significantly affecting overall minute ventilation, while circulatory parameters showed increased amplitude during breathing cycles, indicating a complex interaction between respiration and circulation.
Construction of an animal model of autism based on interaction between cerebellar histological, immunohistochemical, and biochemical changes in adult male albino rat.
Ultrastruct Pathol
January 2025
Department of Medical Histology and Cell Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Methods: Twelve pregnant female rats were divided into a control group and a valproic acid (VPA) treated group (injected intraperitoneally on embryonic day 12 with 600 mg/kg body weight of VPA). Neurobehavioral tests were conducted on the offspring of both groups. The cerebellum was studied by light and electron microscopy as well as GFAP and caspase-3 immunohistochemical staining.
View Article and Find Full Text PDFSand Fly Fauna in Urban Parks in the Brazilian Western Amazon: Potential Areas for American Cutaneous Leishmaniasis Transmission.
Ecohealth
December 2024
Andreia Fernandes Brilhante, Programa de Pós-Graduação em Ciências da Saúde na Amazônia Ocidental, Universidade Federal do Acre, BR 364, KM02, Distrito Industrial, Rio Branco, Acre, 69920-900, Brazil.
Sand flies are a group of insects (Diptera, Psychodidae, Phlebotominae) in which some species may transmit agents of leishmaniasis. This study aimed to analyze the sand fly fauna in urban parks in Rio Branco, capital of Acre state, addressing its diversity, infection by Leishmania, and food sources in sand fly females. The sand flies were collected with CDC-type automatic light traps installed in three urban parks in Rio Branco: Captain Ciríaco, Horto Florestal and Chico Mendes.
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