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Diagnostic Accuracy of Lung and Abdominal Ultrasound for Tuberculosis in a German Multicenter Cohort of Patients With Presumed Tuberculosis Disease.
Open Forum Infect Dis
December 2024
Department for Infectious Disease and Tropical Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Background: There is limited evidence on point-of-care ultrasound for tuberculosis (TB), but studies suggest high sensitivity, especially for lung ultrasound (LUS). However, insufficient data are available on specificity of the examination and its generalizability to a broader patient population.
Aims: Our study aimed to establish accuracy for lung, chest, and abdominal ultrasound, individually and in combination, for TB diagnosis.
Article Synopsis
- HIV significantly affects neurocognitive function in Africa, leading to high prevalence rates of neurocognitive disorders, with Central and South Africa showing the highest impairment levels (around 49.33%).
- Variability in neurocognitive impairment prevalence is influenced by factors like ART availability, healthcare infrastructure, and co-infections, emphasizing the need for targeted interventions.
- Addressing this issue requires collaboration among healthcare providers, policymakers, and communities, focusing on education, early detection, improved resources, and research partnerships to better support individuals living with HIV.
HIV-Associated Pseudoaneurysms: A Comprehensive Review.
Cureus
October 2024
Medicine, King Edward Medical University, Lahore, PAK.
Article Synopsis
- * Symptoms and characteristics of PSAs can vary, making diagnosis important, which can be done using ultrasonography, CT scans, or other imaging techniques.
- * Treatment options for PSAs include surgical methods, ultrasound-guided therapies, and advanced endovascular techniques, along with a discussion of risk factors and potential complications.
HIV causes susceptibility to respiratory pathogens, including tuberculosis (TB), but the underlying immunological mechanisms remain incompletely understood. We obtained whole blood and bronchoalveolar lavage (BAL) from TB-exposed people in the presence or absence of antiretroviral-naïve HIV co-infection. Bulk transcriptional profiling demonstrated compartment-specific enrichment of immunological processes.
View Article and Find Full Text PDFExploring Health-Related Quality of Life (HRQOL) among patients with HIV-associated TB in Khayelitsha, South Africa.
PLoS One
November 2024
Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Background: Health-related quality of life (HRQOL) is an important and frequently used patient-reported outcome in health research. However, little qualitative research exists in this field in South Africa. This study was set in Khayelitsha, one of the largest informal settlements in South Africa, where the burden of HIV and tuberculosis (TB) co-infection are amongst the highest in the world and significantly affect HRQOL.
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